Prevalence and spectrum of abnormal electrocardiograms in patients with an isolated congenital left ventricular aneurysm or diverticulum
Aims Congenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare cardiac anomalies and can be associated with ECG abnormalities and rhythm disturbances. We sought to investigate the prevalence and the spectrum of ECG abnormalities in such patients. Methods and results We assessed 125...
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| Veröffentlicht in: | Europace (London, England) England), 2009-12, Vol.11 (12), p.1689-1695 |
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| creator | Ohlow, Marc-Alexander Lauer, Bernward Geller, J. Christoph |
| description | Aims
Congenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare cardiac anomalies and can be associated with ECG abnormalities and rhythm disturbances. We sought to investigate the prevalence and the spectrum of ECG abnormalities in such patients.
Methods and results
We assessed 125 patients with isolated LVA or LVD for the prevalence of ECG abnormalities and compared the findings to an age- and gender-matched control group. The 12-lead ECG patterns were evaluated according to commonly used criteria and were classified into three subgroups (distinct, mildly, and minor). Fifty-four of the 125 patients (43.2%) had normal and 71 (56.8%) abnormal ECGs. Mean age was 66 years. Forty-nine (39.2%) were male. Distinct abnormal ECG patterns were more prevalent in patients with LVD (38.2 vs. 15.8%, P = 0.04), and apical location of the anomaly (36.6 vs. 16.6%, P = 0.02). Older age (>66 years) was associated with a trend for a higher prevalence of abnormal ECG pattern (33 vs. 18%, P = 0.06), whereas gender had no influence (32 vs. 16%, P = 0.14). This study also shows that the sensitivity, specificity, positive predictive value and negative predictive value of a 12-lead ECG for the diagnosis of LVA or LVD are low.
Conclusion
This large single-centre study suggests that the prevalence of abnormal ECG patterns in patients with isolated LVA or LVD is as high as 56.8%. However, ECG is not specific and sensitive to be used as a screening tool in such patients. |
| doi_str_mv | 10.1093/europace/eup323 |
| format | Article |
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Congenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare cardiac anomalies and can be associated with ECG abnormalities and rhythm disturbances. We sought to investigate the prevalence and the spectrum of ECG abnormalities in such patients.
Methods and results
We assessed 125 patients with isolated LVA or LVD for the prevalence of ECG abnormalities and compared the findings to an age- and gender-matched control group. The 12-lead ECG patterns were evaluated according to commonly used criteria and were classified into three subgroups (distinct, mildly, and minor). Fifty-four of the 125 patients (43.2%) had normal and 71 (56.8%) abnormal ECGs. Mean age was 66 years. Forty-nine (39.2%) were male. Distinct abnormal ECG patterns were more prevalent in patients with LVD (38.2 vs. 15.8%, P = 0.04), and apical location of the anomaly (36.6 vs. 16.6%, P = 0.02). Older age (>66 years) was associated with a trend for a higher prevalence of abnormal ECG pattern (33 vs. 18%, P = 0.06), whereas gender had no influence (32 vs. 16%, P = 0.14). This study also shows that the sensitivity, specificity, positive predictive value and negative predictive value of a 12-lead ECG for the diagnosis of LVA or LVD are low.
Conclusion
This large single-centre study suggests that the prevalence of abnormal ECG patterns in patients with isolated LVA or LVD is as high as 56.8%. However, ECG is not specific and sensitive to be used as a screening tool in such patients.</description><identifier>ISSN: 1099-5129</identifier><identifier>EISSN: 1532-2092</identifier><identifier>DOI: 10.1093/europace/eup323</identifier><identifier>PMID: 19875399</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Arrhythmias, Cardiac - diagnosis ; Arrhythmias, Cardiac - epidemiology ; Comorbidity ; Diverticulum - congenital ; Diverticulum - epidemiology ; Electrocardiography - statistics & numerical data ; Female ; Germany - epidemiology ; Heart Aneurysm - congenital ; Heart Aneurysm - diagnosis ; Heart Aneurysm - epidemiology ; Heart Ventricles - abnormalities ; Humans ; Male ; Middle Aged ; Prevalence ; Risk Assessment ; Risk Factors ; Ventricular Dysfunction, Left - congenital ; Ventricular Dysfunction, Left - diagnosis ; Ventricular Dysfunction, Left - epidemiology</subject><ispartof>Europace (London, England), 2009-12, Vol.11 (12), p.1689-1695</ispartof><rights>Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org. 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-6cdf69a9f6edd6c25299bc67ebe9752505f19f2e343aad97d5911d426fb2b0a53</citedby><cites>FETCH-LOGICAL-c372t-6cdf69a9f6edd6c25299bc67ebe9752505f19f2e343aad97d5911d426fb2b0a53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,1601,27911,27912</link.rule.ids><linktorsrc>$$Uhttps://dx.doi.org/10.1093/europace/eup323$$EView_record_in_Oxford_University_Press$$FView_record_in_$$GOxford_University_Press</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19875399$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ohlow, Marc-Alexander</creatorcontrib><creatorcontrib>Lauer, Bernward</creatorcontrib><creatorcontrib>Geller, J. Christoph</creatorcontrib><title>Prevalence and spectrum of abnormal electrocardiograms in patients with an isolated congenital left ventricular aneurysm or diverticulum</title><title>Europace (London, England)</title><addtitle>Europace</addtitle><description>Aims
Congenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare cardiac anomalies and can be associated with ECG abnormalities and rhythm disturbances. We sought to investigate the prevalence and the spectrum of ECG abnormalities in such patients.
Methods and results
We assessed 125 patients with isolated LVA or LVD for the prevalence of ECG abnormalities and compared the findings to an age- and gender-matched control group. The 12-lead ECG patterns were evaluated according to commonly used criteria and were classified into three subgroups (distinct, mildly, and minor). Fifty-four of the 125 patients (43.2%) had normal and 71 (56.8%) abnormal ECGs. Mean age was 66 years. Forty-nine (39.2%) were male. Distinct abnormal ECG patterns were more prevalent in patients with LVD (38.2 vs. 15.8%, P = 0.04), and apical location of the anomaly (36.6 vs. 16.6%, P = 0.02). Older age (>66 years) was associated with a trend for a higher prevalence of abnormal ECG pattern (33 vs. 18%, P = 0.06), whereas gender had no influence (32 vs. 16%, P = 0.14). This study also shows that the sensitivity, specificity, positive predictive value and negative predictive value of a 12-lead ECG for the diagnosis of LVA or LVD are low.
Conclusion
This large single-centre study suggests that the prevalence of abnormal ECG patterns in patients with isolated LVA or LVD is as high as 56.8%. However, ECG is not specific and sensitive to be used as a screening tool in such patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arrhythmias, Cardiac - diagnosis</subject><subject>Arrhythmias, Cardiac - epidemiology</subject><subject>Comorbidity</subject><subject>Diverticulum - congenital</subject><subject>Diverticulum - epidemiology</subject><subject>Electrocardiography - statistics & numerical data</subject><subject>Female</subject><subject>Germany - epidemiology</subject><subject>Heart Aneurysm - congenital</subject><subject>Heart Aneurysm - diagnosis</subject><subject>Heart Aneurysm - epidemiology</subject><subject>Heart Ventricles - abnormalities</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Ventricular Dysfunction, Left - congenital</subject><subject>Ventricular Dysfunction, Left - diagnosis</subject><subject>Ventricular Dysfunction, Left - epidemiology</subject><issn>1099-5129</issn><issn>1532-2092</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtqHDEQRYWJ8StZexe0Cxja1mPU7VoG4xcY4oWzbtRSaaygbnUk9QT_gT87GmZCll5VUXXureIScs7ZJWcgr3BJcdYGazNLIQ_ICVdSNIKB-FR7BtAoLuCYnOb8izHWCVBH5JjDdackwAl5f0640QEng1RPluYZTUnLSKOjephiGnWgGLbDaHSyPq6THjP1E5118TiVTP_48lrF1OcYdEFLTZzWOPlSpQFdoZuKJW-WoFPl6s9vuR5I1PoNprJdLONncuh0yPhlX8_Iz7vbl5uH5unH_ePN96fGyE6UpjXWtaDBtWhta4QSAINpOxwQOiUUU46DEyhXUmsLnVXAuV2J1g1iYFrJM_Jt5zun-HvBXPrRZ4Mh1MfikvtOypZfM8krebUjTYo5J3T9nPyo01vPWb9Nv_-Xfr9Lvyq-7r2XYUT7n9_HXYGLHRCX-UO3v2R5lvc</recordid><startdate>200912</startdate><enddate>200912</enddate><creator>Ohlow, Marc-Alexander</creator><creator>Lauer, Bernward</creator><creator>Geller, J. Christoph</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200912</creationdate><title>Prevalence and spectrum of abnormal electrocardiograms in patients with an isolated congenital left ventricular aneurysm or diverticulum</title><author>Ohlow, Marc-Alexander ; Lauer, Bernward ; Geller, J. Christoph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-6cdf69a9f6edd6c25299bc67ebe9752505f19f2e343aad97d5911d426fb2b0a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arrhythmias, Cardiac - diagnosis</topic><topic>Arrhythmias, Cardiac - epidemiology</topic><topic>Comorbidity</topic><topic>Diverticulum - congenital</topic><topic>Diverticulum - epidemiology</topic><topic>Electrocardiography - statistics & numerical data</topic><topic>Female</topic><topic>Germany - epidemiology</topic><topic>Heart Aneurysm - congenital</topic><topic>Heart Aneurysm - diagnosis</topic><topic>Heart Aneurysm - epidemiology</topic><topic>Heart Ventricles - abnormalities</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Ventricular Dysfunction, Left - congenital</topic><topic>Ventricular Dysfunction, Left - diagnosis</topic><topic>Ventricular Dysfunction, Left - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ohlow, Marc-Alexander</creatorcontrib><creatorcontrib>Lauer, Bernward</creatorcontrib><creatorcontrib>Geller, J. Christoph</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Europace (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ohlow, Marc-Alexander</au><au>Lauer, Bernward</au><au>Geller, J. Christoph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence and spectrum of abnormal electrocardiograms in patients with an isolated congenital left ventricular aneurysm or diverticulum</atitle><jtitle>Europace (London, England)</jtitle><addtitle>Europace</addtitle><date>2009-12</date><risdate>2009</risdate><volume>11</volume><issue>12</issue><spage>1689</spage><epage>1695</epage><pages>1689-1695</pages><issn>1099-5129</issn><eissn>1532-2092</eissn><abstract>Aims
Congenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare cardiac anomalies and can be associated with ECG abnormalities and rhythm disturbances. We sought to investigate the prevalence and the spectrum of ECG abnormalities in such patients.
Methods and results
We assessed 125 patients with isolated LVA or LVD for the prevalence of ECG abnormalities and compared the findings to an age- and gender-matched control group. The 12-lead ECG patterns were evaluated according to commonly used criteria and were classified into three subgroups (distinct, mildly, and minor). Fifty-four of the 125 patients (43.2%) had normal and 71 (56.8%) abnormal ECGs. Mean age was 66 years. Forty-nine (39.2%) were male. Distinct abnormal ECG patterns were more prevalent in patients with LVD (38.2 vs. 15.8%, P = 0.04), and apical location of the anomaly (36.6 vs. 16.6%, P = 0.02). Older age (>66 years) was associated with a trend for a higher prevalence of abnormal ECG pattern (33 vs. 18%, P = 0.06), whereas gender had no influence (32 vs. 16%, P = 0.14). This study also shows that the sensitivity, specificity, positive predictive value and negative predictive value of a 12-lead ECG for the diagnosis of LVA or LVD are low.
Conclusion
This large single-centre study suggests that the prevalence of abnormal ECG patterns in patients with isolated LVA or LVD is as high as 56.8%. However, ECG is not specific and sensitive to be used as a screening tool in such patients.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>19875399</pmid><doi>10.1093/europace/eup323</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Arrhythmias, Cardiac - diagnosis Arrhythmias, Cardiac - epidemiology Comorbidity Diverticulum - congenital Diverticulum - epidemiology Electrocardiography - statistics & numerical data Female Germany - epidemiology Heart Aneurysm - congenital Heart Aneurysm - diagnosis Heart Aneurysm - epidemiology Heart Ventricles - abnormalities Humans Male Middle Aged Prevalence Risk Assessment Risk Factors Ventricular Dysfunction, Left - congenital Ventricular Dysfunction, Left - diagnosis Ventricular Dysfunction, Left - epidemiology |
| title | Prevalence and spectrum of abnormal electrocardiograms in patients with an isolated congenital left ventricular aneurysm or diverticulum |
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