Serum zinc is decreased in Alzheimer's disease and serum arsenic correlates positively with cognitive ability

Zinc, copper, and iron aggregate Aβ and accumulate in Alzheimer's disease (AD) plaques. Some metals are increased in AD vs. control serum. The authors examined levels of 12 metals in serum of 44 AD and 41 control subjects. Zinc decreased from 12.3 to 10.9 μmol/L (means, p = 0.0007). Arsenic pos...

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Veröffentlicht in:	Biometals 2010-02, Vol.23 (1), p.173-179
Hauptverfasser:	Baum, Larry, Chan, Iris Hiu Shuen, Cheung, Stanley Kwok-Kuen, Goggins, William B, Mok, Vincent, Lam, Linda, Leung, Vivian, Hui, Elsie, Ng, Chelsia, Woo, Jean, Chiu, Helen Fung Kum, Zee, Benny Chung-Ying, Cheng, William, Chan, Ming-Houng, Szeto, Samuel, Lui, Victor, Tsoh, Joshua, Bush, Ashley I, Lam, Christopher Wai Kei, Kwok, Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - blood Alzheimer's disease Arsenic Arsenic - blood Biochemistry Biomedical and Life Sciences Cell Biology Cognition Cognition & reasoning Cognitive ability Correlation analysis Female Humans Life Sciences Male Medicine/Public Health Microbiology Pharmacology/Toxicology Plant Physiology Seafood Zinc Zinc - blood
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