Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome
Background Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSA...
Gespeichert in:
| Veröffentlicht in: | Sleep & breathing 2009-11, Vol.13 (4), p.349-355 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 355 |
|---|---|
| container_issue | 4 |
| container_start_page | 349 |
| container_title | Sleep & breathing |
| container_volume | 13 |
| creator | Trakada, Georgia Steiropoulos, Paschalis Nena, Evangelia Gkioka, Theodora Kouliatsis, Georgios Pataka, Athanasia Sotiriou, Ioannis Anevlavis, Stavros Papanas, Nikolaos Bouros, Demosthenes |
| description | Background
Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSAS and examine their potential correlation with sleep characteristics and several biochemical parameters.
Methods
Nondiabetic patients with severe OSAS (Apnea Hypopnea Index > 30/h,
n
= 32) and healthy controls (Apnea Hypopnea Index |
| doi_str_mv | 10.1007/s11325-009-0254-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733612596</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2387245101</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-cef931a3d522f61546d482948a775fad5f215c75603b460493fa27fa1d652d773</originalsourceid><addsrcrecordid>eNp1kE1qG0EQhRtjY9myD5BNGAzBq7G7-le9DMKxA4J44ayb1kx3MmL-0jUj0C6H8AlzEvdEIoKAV_Wgvnr1eIR8AHoHlOp7BOBM5pSanDIpcnVCLkAyloOm5vSvprmRwGbkEnFDKYiFgXMyA8MVFUJdkNVz7bBx2bbC4IaqzWq_9TVmSWFS0WfdGoc4FkO19RnW3veZ61vv_vx-_bnru0lmuGvL2DX-ipwFV6O_Psw5-f7l4WX5lK--PX5dfl7lhaB0yAsfDAfHyxQ1KJBClWLBjFg4rWVwpQwMZKGlonwtUk7Dg2M6OCiVZKXWfE5u97597H6NHgfbVFj4unat70a0mnMFTBqVyJv_yE03xjaFswstQBgBMkGwh4rYIUYfbB-rxsWdBWqnou2-aJuKtlPRdjL-eDAe140vjxeHZhPw6QA4LFwdomuLCv9xjCVLI6fnbM9hWrU_fDwmfP_7G0STlV8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>874149415</pqid></control><display><type>article</type><title>Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Trakada, Georgia ; Steiropoulos, Paschalis ; Nena, Evangelia ; Gkioka, Theodora ; Kouliatsis, Georgios ; Pataka, Athanasia ; Sotiriou, Ioannis ; Anevlavis, Stavros ; Papanas, Nikolaos ; Bouros, Demosthenes</creator><creatorcontrib>Trakada, Georgia ; Steiropoulos, Paschalis ; Nena, Evangelia ; Gkioka, Theodora ; Kouliatsis, Georgios ; Pataka, Athanasia ; Sotiriou, Ioannis ; Anevlavis, Stavros ; Papanas, Nikolaos ; Bouros, Demosthenes</creatorcontrib><description>Background
Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSAS and examine their potential correlation with sleep characteristics and several biochemical parameters.
Methods
Nondiabetic patients with severe OSAS (Apnea Hypopnea Index > 30/h,
n
= 32) and healthy controls (Apnea Hypopnea Index < 5/h,
n
= 12), examined with polysomnography, underwent a biochemical analysis to estimate fasting levels of visfatin, glucose, insulin, C-peptide, and lipid profile.
Results
The two groups were matched for age and body mass index (BMI). OSAS patients had significantly higher fasting insulin levels (
p
= 0.045), but no difference was shown in visfatin between patients and controls (
p
= 0.585). In OSAS patients, visfatin levels correlated positively with sleep latency (
r
= 0.539,
p
= 0.01) and triglyceride levels (
r
= 0.584,
p
= 0.036) and negatively with total sleep time, percentage of stage 2 and REM sleep, and LDL-cholesterol levels (
r
= −0.659 and
p
= 0.001;
r
= −0.496 and
p
= 0.019;
r
= −0.577 and
p
= 0.005;
r
= −0.804
and p
= 0.003, respectively). No association was found, however, between visfatin levels and HOMA index or indices of nocturnal hypoxia.
Conclusions
In patients with severe OSAS, visfatin levels are associated with characteristics of sleep architecture. However, there is no correlation between visfatin and insulin resistance or nocturnal hypoxia.</description><identifier>ISSN: 1520-9512</identifier><identifier>EISSN: 1522-1709</identifier><identifier>DOI: 10.1007/s11325-009-0254-6</identifier><identifier>PMID: 19360446</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Biological and medical sciences ; Blood Glucose - metabolism ; Body Mass Index ; C-Peptide - blood ; Cholesterol, HDL - blood ; Cholesterol, LDL - blood ; Dentistry ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Female ; Fundamental and applied biological sciences. Psychology ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Humans ; Hypoxia ; Insulin resistance ; Insulin Resistance - physiology ; Internal Medicine ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Nervous system (semeiology, syndromes) ; Neurology ; Nicotinamide Phosphoribosyltransferase - blood ; Original Article ; Otorhinolaryngology ; Pediatrics ; Plasma ; Pneumology/Respiratory System ; Polysomnography ; Sleep apnea ; Sleep Apnea, Obstructive - blood ; Sleep disorders ; Sleep Stages - physiology ; Sleep, REM - physiology ; Sleep. Vigilance ; Statistics as Topic ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the upper aerodigestive tract ; Triglycerides - blood ; Vertebrates: nervous system and sense organs</subject><ispartof>Sleep & breathing, 2009-11, Vol.13 (4), p.349-355</ispartof><rights>Springer-Verlag 2009</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-cef931a3d522f61546d482948a775fad5f215c75603b460493fa27fa1d652d773</citedby><cites>FETCH-LOGICAL-c400t-cef931a3d522f61546d482948a775fad5f215c75603b460493fa27fa1d652d773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11325-009-0254-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11325-009-0254-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22113955$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19360446$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Trakada, Georgia</creatorcontrib><creatorcontrib>Steiropoulos, Paschalis</creatorcontrib><creatorcontrib>Nena, Evangelia</creatorcontrib><creatorcontrib>Gkioka, Theodora</creatorcontrib><creatorcontrib>Kouliatsis, Georgios</creatorcontrib><creatorcontrib>Pataka, Athanasia</creatorcontrib><creatorcontrib>Sotiriou, Ioannis</creatorcontrib><creatorcontrib>Anevlavis, Stavros</creatorcontrib><creatorcontrib>Papanas, Nikolaos</creatorcontrib><creatorcontrib>Bouros, Demosthenes</creatorcontrib><title>Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome</title><title>Sleep & breathing</title><addtitle>Sleep Breath</addtitle><addtitle>Sleep Breath</addtitle><description>Background
Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSAS and examine their potential correlation with sleep characteristics and several biochemical parameters.
Methods
Nondiabetic patients with severe OSAS (Apnea Hypopnea Index > 30/h,
n
= 32) and healthy controls (Apnea Hypopnea Index < 5/h,
n
= 12), examined with polysomnography, underwent a biochemical analysis to estimate fasting levels of visfatin, glucose, insulin, C-peptide, and lipid profile.
Results
The two groups were matched for age and body mass index (BMI). OSAS patients had significantly higher fasting insulin levels (
p
= 0.045), but no difference was shown in visfatin between patients and controls (
p
= 0.585). In OSAS patients, visfatin levels correlated positively with sleep latency (
r
= 0.539,
p
= 0.01) and triglyceride levels (
r
= 0.584,
p
= 0.036) and negatively with total sleep time, percentage of stage 2 and REM sleep, and LDL-cholesterol levels (
r
= −0.659 and
p
= 0.001;
r
= −0.496 and
p
= 0.019;
r
= −0.577 and
p
= 0.005;
r
= −0.804
and p
= 0.003, respectively). No association was found, however, between visfatin levels and HOMA index or indices of nocturnal hypoxia.
Conclusions
In patients with severe OSAS, visfatin levels are associated with characteristics of sleep architecture. However, there is no correlation between visfatin and insulin resistance or nocturnal hypoxia.</description><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Body Mass Index</subject><subject>C-Peptide - blood</subject><subject>Cholesterol, HDL - blood</subject><subject>Cholesterol, LDL - blood</subject><subject>Dentistry</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Humans</subject><subject>Hypoxia</subject><subject>Insulin resistance</subject><subject>Insulin Resistance - physiology</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Nicotinamide Phosphoribosyltransferase - blood</subject><subject>Original Article</subject><subject>Otorhinolaryngology</subject><subject>Pediatrics</subject><subject>Plasma</subject><subject>Pneumology/Respiratory System</subject><subject>Polysomnography</subject><subject>Sleep apnea</subject><subject>Sleep Apnea, Obstructive - blood</subject><subject>Sleep disorders</subject><subject>Sleep Stages - physiology</subject><subject>Sleep, REM - physiology</subject><subject>Sleep. Vigilance</subject><subject>Statistics as Topic</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the upper aerodigestive tract</subject><subject>Triglycerides - blood</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>1520-9512</issn><issn>1522-1709</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kE1qG0EQhRtjY9myD5BNGAzBq7G7-le9DMKxA4J44ayb1kx3MmL-0jUj0C6H8AlzEvdEIoKAV_Wgvnr1eIR8AHoHlOp7BOBM5pSanDIpcnVCLkAyloOm5vSvprmRwGbkEnFDKYiFgXMyA8MVFUJdkNVz7bBx2bbC4IaqzWq_9TVmSWFS0WfdGoc4FkO19RnW3veZ61vv_vx-_bnru0lmuGvL2DX-ipwFV6O_Psw5-f7l4WX5lK--PX5dfl7lhaB0yAsfDAfHyxQ1KJBClWLBjFg4rWVwpQwMZKGlonwtUk7Dg2M6OCiVZKXWfE5u97597H6NHgfbVFj4unat70a0mnMFTBqVyJv_yE03xjaFswstQBgBMkGwh4rYIUYfbB-rxsWdBWqnou2-aJuKtlPRdjL-eDAe140vjxeHZhPw6QA4LFwdomuLCv9xjCVLI6fnbM9hWrU_fDwmfP_7G0STlV8</recordid><startdate>20091101</startdate><enddate>20091101</enddate><creator>Trakada, Georgia</creator><creator>Steiropoulos, Paschalis</creator><creator>Nena, Evangelia</creator><creator>Gkioka, Theodora</creator><creator>Kouliatsis, Georgios</creator><creator>Pataka, Athanasia</creator><creator>Sotiriou, Ioannis</creator><creator>Anevlavis, Stavros</creator><creator>Papanas, Nikolaos</creator><creator>Bouros, Demosthenes</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7T5</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2R</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20091101</creationdate><title>Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome</title><author>Trakada, Georgia ; Steiropoulos, Paschalis ; Nena, Evangelia ; Gkioka, Theodora ; Kouliatsis, Georgios ; Pataka, Athanasia ; Sotiriou, Ioannis ; Anevlavis, Stavros ; Papanas, Nikolaos ; Bouros, Demosthenes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-cef931a3d522f61546d482948a775fad5f215c75603b460493fa27fa1d652d773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Biological and medical sciences</topic><topic>Blood Glucose - metabolism</topic><topic>Body Mass Index</topic><topic>C-Peptide - blood</topic><topic>Cholesterol, HDL - blood</topic><topic>Cholesterol, LDL - blood</topic><topic>Dentistry</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</topic><topic>Humans</topic><topic>Hypoxia</topic><topic>Insulin resistance</topic><topic>Insulin Resistance - physiology</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Nicotinamide Phosphoribosyltransferase - blood</topic><topic>Original Article</topic><topic>Otorhinolaryngology</topic><topic>Pediatrics</topic><topic>Plasma</topic><topic>Pneumology/Respiratory System</topic><topic>Polysomnography</topic><topic>Sleep apnea</topic><topic>Sleep Apnea, Obstructive - blood</topic><topic>Sleep disorders</topic><topic>Sleep Stages - physiology</topic><topic>Sleep, REM - physiology</topic><topic>Sleep. Vigilance</topic><topic>Statistics as Topic</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the upper aerodigestive tract</topic><topic>Triglycerides - blood</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Trakada, Georgia</creatorcontrib><creatorcontrib>Steiropoulos, Paschalis</creatorcontrib><creatorcontrib>Nena, Evangelia</creatorcontrib><creatorcontrib>Gkioka, Theodora</creatorcontrib><creatorcontrib>Kouliatsis, Georgios</creatorcontrib><creatorcontrib>Pataka, Athanasia</creatorcontrib><creatorcontrib>Sotiriou, Ioannis</creatorcontrib><creatorcontrib>Anevlavis, Stavros</creatorcontrib><creatorcontrib>Papanas, Nikolaos</creatorcontrib><creatorcontrib>Bouros, Demosthenes</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Social Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep & breathing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Trakada, Georgia</au><au>Steiropoulos, Paschalis</au><au>Nena, Evangelia</au><au>Gkioka, Theodora</au><au>Kouliatsis, Georgios</au><au>Pataka, Athanasia</au><au>Sotiriou, Ioannis</au><au>Anevlavis, Stavros</au><au>Papanas, Nikolaos</au><au>Bouros, Demosthenes</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome</atitle><jtitle>Sleep & breathing</jtitle><stitle>Sleep Breath</stitle><addtitle>Sleep Breath</addtitle><date>2009-11-01</date><risdate>2009</risdate><volume>13</volume><issue>4</issue><spage>349</spage><epage>355</epage><pages>349-355</pages><issn>1520-9512</issn><eissn>1522-1709</eissn><abstract>Background
Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSAS and examine their potential correlation with sleep characteristics and several biochemical parameters.
Methods
Nondiabetic patients with severe OSAS (Apnea Hypopnea Index > 30/h,
n
= 32) and healthy controls (Apnea Hypopnea Index < 5/h,
n
= 12), examined with polysomnography, underwent a biochemical analysis to estimate fasting levels of visfatin, glucose, insulin, C-peptide, and lipid profile.
Results
The two groups were matched for age and body mass index (BMI). OSAS patients had significantly higher fasting insulin levels (
p
= 0.045), but no difference was shown in visfatin between patients and controls (
p
= 0.585). In OSAS patients, visfatin levels correlated positively with sleep latency (
r
= 0.539,
p
= 0.01) and triglyceride levels (
r
= 0.584,
p
= 0.036) and negatively with total sleep time, percentage of stage 2 and REM sleep, and LDL-cholesterol levels (
r
= −0.659 and
p
= 0.001;
r
= −0.496 and
p
= 0.019;
r
= −0.577 and
p
= 0.005;
r
= −0.804
and p
= 0.003, respectively). No association was found, however, between visfatin levels and HOMA index or indices of nocturnal hypoxia.
Conclusions
In patients with severe OSAS, visfatin levels are associated with characteristics of sleep architecture. However, there is no correlation between visfatin and insulin resistance or nocturnal hypoxia.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>19360446</pmid><doi>10.1007/s11325-009-0254-6</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1520-9512 |
| ispartof | Sleep & breathing, 2009-11, Vol.13 (4), p.349-355 |
| issn | 1520-9512 1522-1709 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_733612596 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Biological and medical sciences Blood Glucose - metabolism Body Mass Index C-Peptide - blood Cholesterol, HDL - blood Cholesterol, LDL - blood Dentistry Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Female Fundamental and applied biological sciences. Psychology Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Humans Hypoxia Insulin resistance Insulin Resistance - physiology Internal Medicine Male Medical sciences Medicine Medicine & Public Health Middle Aged Nervous system (semeiology, syndromes) Neurology Nicotinamide Phosphoribosyltransferase - blood Original Article Otorhinolaryngology Pediatrics Plasma Pneumology/Respiratory System Polysomnography Sleep apnea Sleep Apnea, Obstructive - blood Sleep disorders Sleep Stages - physiology Sleep, REM - physiology Sleep. Vigilance Statistics as Topic Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Triglycerides - blood Vertebrates: nervous system and sense organs |
| title | Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T00%3A48%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Plasma%20visfatin%20levels%20in%20severe%20obstructive%20sleep%20apnea%E2%80%94hypopnea%20syndrome&rft.jtitle=Sleep%20&%20breathing&rft.au=Trakada,%20Georgia&rft.date=2009-11-01&rft.volume=13&rft.issue=4&rft.spage=349&rft.epage=355&rft.pages=349-355&rft.issn=1520-9512&rft.eissn=1522-1709&rft_id=info:doi/10.1007/s11325-009-0254-6&rft_dat=%3Cproquest_cross%3E2387245101%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=874149415&rft_id=info:pmid/19360446&rfr_iscdi=true |