Plasma visfatin levels in severe obstructive sleep apnea—hypopnea syndrome

Background Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSA...

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Veröffentlicht in:	Sleep & breathing 2009-11, Vol.13 (4), p.349-355
Hauptverfasser:	Trakada, Georgia, Steiropoulos, Paschalis, Nena, Evangelia, Gkioka, Theodora, Kouliatsis, Georgios, Pataka, Athanasia, Sotiriou, Ioannis, Anevlavis, Stavros, Papanas, Nikolaos, Bouros, Demosthenes
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Glucose - metabolism Body Mass Index C-Peptide - blood Cholesterol, HDL - blood Cholesterol, LDL - blood Dentistry Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Female Fundamental and applied biological sciences. Psychology Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Humans Hypoxia Insulin resistance Insulin Resistance - physiology Internal Medicine Male Medical sciences Medicine Medicine & Public Health Middle Aged Nervous system (semeiology, syndromes) Neurology Nicotinamide Phosphoribosyltransferase - blood Original Article Otorhinolaryngology Pediatrics Plasma Pneumology/Respiratory System Polysomnography Sleep apnea Sleep Apnea, Obstructive - blood Sleep disorders Sleep Stages - physiology Sleep, REM - physiology Sleep. Vigilance Statistics as Topic Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Triglycerides - blood Vertebrates: nervous system and sense organs
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Zusammenfassung:	Background Obstructive sleep apnea syndrome (OSAS) is associated with obesity and insulin resistance. Visfatin is an insulin-mimicking adipokine, which is considered a link between obesity and insulin resistance. Aim of this study was to evaluate levels of plasma visfatin in patients with severe OSAS and examine their potential correlation with sleep characteristics and several biochemical parameters. Methods Nondiabetic patients with severe OSAS (Apnea Hypopnea Index > 30/h, n = 32) and healthy controls (Apnea Hypopnea Index
ISSN:	1520-9512 1522-1709
DOI:	10.1007/s11325-009-0254-6