Anti-angiogenic actions of pyrrolidine dithiocarbamate, a nuclear factor kappa B inhibitor

Renal cell carcinomas (RCC) are a heterogeneous group of cancers that often include angiogenesis as a key clinical and pathological hallmark. As the transcription factor nuclear factor kappa B (NF-κB) has been identified as a key promoter of angiogenesis, NF-κB inhibitors could serve as potential an...

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Veröffentlicht in:Angiogenesis (London) 2009-12, Vol.12 (4), p.365-379
Hauptverfasser: Morais, Christudas, Gobe, Glenda, Johnson, David W., Healy, Helen
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Sprache:eng
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