Severe systemic lupus erythematosus induced by isoniazide
The authors report a rare case of low register systemic lupus erythematosus with renal attack and neurological armature by isoniazid. The patient was a 23-year-old woman presenting a lupus induced by isoniazid 1 month after the treatment of pleural tuberculosis. Antinuclear antibodies, anti-native D...
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| Veröffentlicht in: | Revue de pneumologie clinique 2009-12, Vol.65 (6), p.361-364 |
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| container_title | Revue de pneumologie clinique |
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| creator | Rakotoson, J L Randriamanana, D Rakotomizao, J R Andrianasolo, R Rakotoarivelo, R Andrianarisoa, A C F |
| description | The authors report a rare case of low register systemic lupus erythematosus with renal attack and neurological armature by isoniazid. The patient was a 23-year-old woman presenting a lupus induced by isoniazid 1 month after the treatment of pleural tuberculosis. Antinuclear antibodies, anti-native DNA, anti-ENA, anti-Sm, anti-SSa, anti-SSb and antihistone were present. The symptoms included arthralgia, fever, anaemia, pleural effusion, pericarditis and anasarca. She presented a renal and neurological attack, accounting for the gravity of the disease. The treatment consisted of the interruption of the isoniazid and a bolus of methyl-prednisolone during 3 days relayed by an oral corticosteroid. The evolution was favourable after 8 months of corticosteroids. |
| doi_str_mv | 10.1016/j.pneumo.2009.08.006 |
| format | Article |
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The patient was a 23-year-old woman presenting a lupus induced by isoniazid 1 month after the treatment of pleural tuberculosis. Antinuclear antibodies, anti-native DNA, anti-ENA, anti-Sm, anti-SSa, anti-SSb and antihistone were present. The symptoms included arthralgia, fever, anaemia, pleural effusion, pericarditis and anasarca. She presented a renal and neurological attack, accounting for the gravity of the disease. The treatment consisted of the interruption of the isoniazid and a bolus of methyl-prednisolone during 3 days relayed by an oral corticosteroid. 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The patient was a 23-year-old woman presenting a lupus induced by isoniazid 1 month after the treatment of pleural tuberculosis. Antinuclear antibodies, anti-native DNA, anti-ENA, anti-Sm, anti-SSa, anti-SSb and antihistone were present. The symptoms included arthralgia, fever, anaemia, pleural effusion, pericarditis and anasarca. She presented a renal and neurological attack, accounting for the gravity of the disease. The treatment consisted of the interruption of the isoniazid and a bolus of methyl-prednisolone during 3 days relayed by an oral corticosteroid. 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| ispartof | Revue de pneumologie clinique, 2009-12, Vol.65 (6), p.361-364 |
| issn | 0761-8417 |
| language | fre |
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| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | Anti-Inflammatory Agents - therapeutic use Antibodies, Antinuclear - blood Antitubercular Agents - adverse effects Antitubercular Agents - therapeutic use Drug Therapy, Combination Female Humans Isoniazid - adverse effects Isoniazid - therapeutic use Lupus Erythematosus, Systemic - chemically induced Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - drug therapy Lupus Nephritis - chemically induced Lupus Nephritis - diagnosis Lupus Nephritis - drug therapy Madagascar Methylprednisolone - therapeutic use Tuberculosis, Pleural - drug therapy Young Adult |
| title | Severe systemic lupus erythematosus induced by isoniazide |
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