Long- but not short-term multifactorial intervention with focus on exercise training improves coronary endothelial dysfunction in diabetes mellitus type 2 and coronary artery disease

Aims Patients with type 2 diabetes mellitus (T2DM) suffer from accelerated coronary artery disease. We assessed the effects of a multifactorial intervention with focus on exercise training on coronary endothelial function, vascular structure, and inflammation in serum and skeletal muscle biopsies, i...

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Veröffentlicht in:	European heart journal 2010-01, Vol.31 (1), p.112-119
Hauptverfasser:	Sixt, Sebastian, Beer, Sebastian, Blüher, Matthias, Korff, Nicolai, Peschel, Thomas, Sonnabend, Melanie, Teupser, Daniel, Thiery, Joachim, Adams, Volker, Schuler, Gerhard, Niebauer, Josef
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - blood Blood Glucose - metabolism Body Weight Coronary Artery Disease - metabolism Coronary Artery Disease - physiopathology Coronary Artery Disease - therapy Coronary endothelial function Diabetes mellitus Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Diabetes Mellitus, Type 2 - therapy Diabetic Angiopathies - therapy Dyslipidemias - therapy Endothelium, Vascular - physiopathology Exercise Therapy - methods Exercise training Female Humans Intracoronary ultrasound Lipid Metabolism Male Muscle, Skeletal - metabolism RNA, Messenger - metabolism Skeletal muscle Ultrasonography, Interventional
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