VEGFR2 is selectively expressed by FOXP3high CD4⁺ Treg

CD25⁺ FOXP3⁺CD4⁺ T cells (Treg) have been considered to play an important role in immune tolerance against several tumor antigens. It has also been indicated that high-level expression of FOXP3 (FOXP3high) is sufficient to confer suppressive activity to normal non-Treg. Here, we showed for the first...

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Veröffentlicht in:	European journal of immunology 2010-01, Vol.40 (1), p.197-203
Hauptverfasser:	Suzuki, Hiroyuki, Onishi, Hideya, Wada, Junji, Yamasaki, Akio, Tanaka, Haruo, Nakano, Kenji, Morisaki, Takashi, Katano, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Forkhead Transcription Factors - immunology FOXP3 Humans Immunotherapy Neoplasms - immunology Neoplasms - therapy T-Lymphocytes, Regulatory - immunology Transforming Growth Factor beta - immunology Treg Vascular Endothelial Growth Factor Receptor-2 - immunology VEGFR2
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