Cytogenetics of neurofibromas: two case reports and literature review
Abstract Only a few karyotypes of neurofibromas have been documented in the literature. In this report, we describe two new cases in which conventional cytogenetics demonstrated the presence of abnormal clones. Combining karyotypes of the nine previously reported cases, we found that the most freque...
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| Veröffentlicht in: | Cancer genetics and cytogenetics 2010, Vol.196 (1), p.93-95 |
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| container_title | Cancer genetics and cytogenetics |
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| creator | Liu, Kenian DeAngelo, Patricia Mahmet, Kathleen Phytides, Penny Osborne, Lisa Pletcher, Beth A |
| description | Abstract Only a few karyotypes of neurofibromas have been documented in the literature. In this report, we describe two new cases in which conventional cytogenetics demonstrated the presence of abnormal clones. Combining karyotypes of the nine previously reported cases, we found that the most frequent structural rearrangements involved chromosome 9p. Including the two cases reported here, 5/11 cases involved 9p, and four of these involved the 9p21∼p22 region. |
| doi_str_mv | 10.1016/j.cancergencyto.2009.07.004 |
| format | Article |
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In this report, we describe two new cases in which conventional cytogenetics demonstrated the presence of abnormal clones. Combining karyotypes of the nine previously reported cases, we found that the most frequent structural rearrangements involved chromosome 9p. 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| ispartof | Cancer genetics and cytogenetics, 2010, Vol.196 (1), p.93-95 |
| issn | 0165-4608 1873-4456 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adolescent Adult Female Hematology, Oncology and Palliative Medicine Humans Karyotyping Male Medical Education Neurofibroma - genetics |
| title | Cytogenetics of neurofibromas: two case reports and literature review |
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