Xenon Attenuates Excitatory Synaptic Transmission in the Rodent Prefrontal Cortex and Spinal Cord Dorsal Horn

The molecular mechanisms of the inhalational anesthetic xenon are not yet fully understood. Recently, the authors showed that xenon reduces both N-methyl-d-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor-mediated synaptic transmission in a brain slice pr...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2009-12, Vol.111 (6), p.1297-1307
Hauptverfasser:	HASENEDER, Rainer, KRATZER, Stephan, KOCHS, Eberhard, MATTUSCH, Corinna, EDER, Matthias, RAMMES, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Inhalation Animals Biological and medical sciences Electric Stimulation Excitatory Postsynaptic Potentials - drug effects In Vitro Techniques Male Medical sciences Mice Mice, Inbred C57BL Pain - physiopathology Posterior Horn Cells - drug effects Prefrontal Cortex - drug effects Receptors, AMPA - drug effects Receptors, GABA-A - drug effects Receptors, N-Methyl-D-Aspartate - drug effects Spinal Cord - drug effects Synaptic Transmission - drug effects Xenon
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