Immunohistochemical localization of the rabbit haemorrhagic disease viral antigen

Immunohistochemical investigations were carried out to determine organ and cellular localization of the rabbit haemorrhagic disease viral antigen (RHDVA). It was found in certain parenchymal liver cells near the interlobular septs and in some macrophages and pseudoeosinophils of all studied organs a...

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Veröffentlicht in:Archives of virology 1992, Vol.127 (1/4), p.355-363
Hauptverfasser: Alexandrov, M, Peshev, R, Yanchev, I, Bozhkov, S, Doumanova, L, Dimitrov, T, Zacharieva, S
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container_end_page 363
container_issue 1/4
container_start_page 355
container_title Archives of virology
container_volume 127
creator Alexandrov, M
Peshev, R
Yanchev, I
Bozhkov, S
Doumanova, L
Dimitrov, T
Zacharieva, S
description Immunohistochemical investigations were carried out to determine organ and cellular localization of the rabbit haemorrhagic disease viral antigen (RHDVA). It was found in certain parenchymal liver cells near the interlobular septs and in some macrophages and pseudoeosinophils of all studied organs and blood. Whereas in morphologically preserved hepatocytes and macrophages the RHDVA accumulated in the nuclei, in cells with disintegrated nuclei it was distributed throughout the cytoplasm.
doi_str_mv 10.1007/BF01309598
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subjects animal organs
Animals
antigens
Antigens, Viral - chemistry
Antigens, Viral - metabolism
Biological and medical sciences
Blotting, Western
Caliciviridae - immunology
Caliciviridae Infections - immunology
Caliciviridae Infections - veterinary
Fundamental and applied biological sciences. Psychology
Hemorrhage - microbiology
Hemorrhage - veterinary
histopathology
Immunohistochemistry
Microbiology
Microscopy, Electron
Molecular Weight
rabbit diseases
rabbit hemorrhagic disease virus
rabbits
Rabbits - microbiology
Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains
Virology
title Immunohistochemical localization of the rabbit haemorrhagic disease viral antigen
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