Immunohistochemical localization of the rabbit haemorrhagic disease viral antigen

Immunohistochemical investigations were carried out to determine organ and cellular localization of the rabbit haemorrhagic disease viral antigen (RHDVA). It was found in certain parenchymal liver cells near the interlobular septs and in some macrophages and pseudoeosinophils of all studied organs a...

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Veröffentlicht in:Archives of virology 1992, Vol.127 (1/4), p.355-363
Hauptverfasser: Alexandrov, M, Peshev, R, Yanchev, I, Bozhkov, S, Doumanova, L, Dimitrov, T, Zacharieva, S
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Sprache:eng
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Zusammenfassung:Immunohistochemical investigations were carried out to determine organ and cellular localization of the rabbit haemorrhagic disease viral antigen (RHDVA). It was found in certain parenchymal liver cells near the interlobular septs and in some macrophages and pseudoeosinophils of all studied organs and blood. Whereas in morphologically preserved hepatocytes and macrophages the RHDVA accumulated in the nuclei, in cells with disintegrated nuclei it was distributed throughout the cytoplasm.
ISSN:0304-8608
1432-8798
DOI:10.1007/BF01309598