A survey of consultant members of the British Association of Oral and Maxillofacial Surgeons regarding bisphosphonate-induced osteonecrosis of the jaws
Abstract The aims of this survey of consultants in the British Association of Oral and Maxillofacial Surgeons were threefold. Firstly, to estimate the number of patients screened for oral health before starting intravenous bisphosphonate medication, secondly, to indicate the use of antibiotics in pa...
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Veröffentlicht in: | British journal of oral & maxillofacial surgery 2009-12, Vol.47 (8), p.598-601 |
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description | Abstract The aims of this survey of consultants in the British Association of Oral and Maxillofacial Surgeons were threefold. Firstly, to estimate the number of patients screened for oral health before starting intravenous bisphosphonate medication, secondly, to indicate the use of antibiotics in patients on bisphosphonates who need routine extraction of a lower first molar tooth, and finally to estimate the number of new and currently managed cases of bisphosphonate-induced osteonecrosis of the jaw (BONJ) in the last year, and approximately how many of those currently being managed had healed. A questionnaire was mailed to 322 consultants working at 154 hospitals in the summer of 2008. There were responses from 184 consultants (57%) and from 111 hospitals (72%). Screening patients before starting intravenous bisphosphonates was uncommon (15%). Almost all consultants would prescribe antibiotics for molar extraction and in about two-thirds this was both before and after extraction. Relatively few would stop bisphosphonates. Nearly two-thirds of consultants had seen new cases of BONJ from intravenous treatment in the last year, and a quarter had seen three or more. A similar proportion had patients on intravenous bisphosphonates under review for BONJ, and it was estimated that in a fifth of patients the lesion had healed. This survey indicates current practice among oral and maxillofacial surgeons in the UK. A national project for the registration of new patients will provide a stronger evidence base with respect to incidence, risk factors, and management of BONJ. |
doi_str_mv | 10.1016/j.bjoms.2009.07.020 |
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Firstly, to estimate the number of patients screened for oral health before starting intravenous bisphosphonate medication, secondly, to indicate the use of antibiotics in patients on bisphosphonates who need routine extraction of a lower first molar tooth, and finally to estimate the number of new and currently managed cases of bisphosphonate-induced osteonecrosis of the jaw (BONJ) in the last year, and approximately how many of those currently being managed had healed. A questionnaire was mailed to 322 consultants working at 154 hospitals in the summer of 2008. There were responses from 184 consultants (57%) and from 111 hospitals (72%). Screening patients before starting intravenous bisphosphonates was uncommon (15%). Almost all consultants would prescribe antibiotics for molar extraction and in about two-thirds this was both before and after extraction. Relatively few would stop bisphosphonates. Nearly two-thirds of consultants had seen new cases of BONJ from intravenous treatment in the last year, and a quarter had seen three or more. A similar proportion had patients on intravenous bisphosphonates under review for BONJ, and it was estimated that in a fifth of patients the lesion had healed. This survey indicates current practice among oral and maxillofacial surgeons in the UK. A national project for the registration of new patients will provide a stronger evidence base with respect to incidence, risk factors, and management of BONJ.</description><identifier>ISSN: 0266-4356</identifier><identifier>EISSN: 1532-1940</identifier><identifier>DOI: 10.1016/j.bjoms.2009.07.020</identifier><identifier>PMID: 19748711</identifier><identifier>CODEN: BJOSEY</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Administration, Oral ; Anti-Infective Agents, Local - administration & dosage ; Anti-Infective Agents, Local - therapeutic use ; Antibiotic Prophylaxis ; Attitude of Health Personnel ; Biological and medical sciences ; Bisphosphonate-induced osteonecrosis of the jaws ; Bisphosphonates ; Bone Density Conservation Agents - administration & dosage ; Bone Density Conservation Agents - adverse effects ; Bones, joints and connective tissue. Antiinflammatory agents ; British Association of Oral and Maxillofacial Surgeons ; Chlorhexidine - administration & dosage ; Chlorhexidine - therapeutic use ; Dental Service, Hospital ; Dentistry ; Diphosphonates - administration & dosage ; Diphosphonates - adverse effects ; Diseases of the osteoarticular system ; Humans ; Injections, Intravenous ; Jaw Diseases - chemically induced ; Jaw Diseases - psychology ; Jaw Diseases - therapy ; Mass Screening ; Medical sciences ; Molar - surgery ; Osteonecrosis - chemically induced ; Osteonecrosis - psychology ; Osteonecrosis - therapy ; Otorhinolaryngology. Stomatology ; Pharmacology. Drug treatments ; Practice Patterns, Dentists ; Societies, Dental ; Surgery ; Surgery, Oral ; Survey ; Surveys and Questionnaires ; Time Factors ; Tooth Extraction ; Tooth Socket - physiology ; United Kingdom ; Vascular bone diseases ; Wound Healing - physiology</subject><ispartof>British journal of oral & maxillofacial surgery, 2009-12, Vol.47 (8), p.598-601</ispartof><rights>2009</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c469t-1cfb5e9526ddc40919882a6b54be438a1aca603c26835d9875bffc3fe2814a743</citedby><cites>FETCH-LOGICAL-c469t-1cfb5e9526ddc40919882a6b54be438a1aca603c26835d9875bffc3fe2814a743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0266435609004835$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22224988$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19748711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rogers, S.N</creatorcontrib><creatorcontrib>Hung, J</creatorcontrib><creatorcontrib>Barber, A.J</creatorcontrib><creatorcontrib>Lowe, D</creatorcontrib><title>A survey of consultant members of the British Association of Oral and Maxillofacial Surgeons regarding bisphosphonate-induced osteonecrosis of the jaws</title><title>British journal of oral & maxillofacial surgery</title><addtitle>Br J Oral Maxillofac Surg</addtitle><description>Abstract The aims of this survey of consultants in the British Association of Oral and Maxillofacial Surgeons were threefold. Firstly, to estimate the number of patients screened for oral health before starting intravenous bisphosphonate medication, secondly, to indicate the use of antibiotics in patients on bisphosphonates who need routine extraction of a lower first molar tooth, and finally to estimate the number of new and currently managed cases of bisphosphonate-induced osteonecrosis of the jaw (BONJ) in the last year, and approximately how many of those currently being managed had healed. A questionnaire was mailed to 322 consultants working at 154 hospitals in the summer of 2008. There were responses from 184 consultants (57%) and from 111 hospitals (72%). Screening patients before starting intravenous bisphosphonates was uncommon (15%). Almost all consultants would prescribe antibiotics for molar extraction and in about two-thirds this was both before and after extraction. Relatively few would stop bisphosphonates. Nearly two-thirds of consultants had seen new cases of BONJ from intravenous treatment in the last year, and a quarter had seen three or more. A similar proportion had patients on intravenous bisphosphonates under review for BONJ, and it was estimated that in a fifth of patients the lesion had healed. This survey indicates current practice among oral and maxillofacial surgeons in the UK. A national project for the registration of new patients will provide a stronger evidence base with respect to incidence, risk factors, and management of BONJ.</description><subject>Administration, Oral</subject><subject>Anti-Infective Agents, Local - administration & dosage</subject><subject>Anti-Infective Agents, Local - therapeutic use</subject><subject>Antibiotic Prophylaxis</subject><subject>Attitude of Health Personnel</subject><subject>Biological and medical sciences</subject><subject>Bisphosphonate-induced osteonecrosis of the jaws</subject><subject>Bisphosphonates</subject><subject>Bone Density Conservation Agents - administration & dosage</subject><subject>Bone Density Conservation Agents - adverse effects</subject><subject>Bones, joints and connective tissue. Antiinflammatory agents</subject><subject>British Association of Oral and Maxillofacial Surgeons</subject><subject>Chlorhexidine - administration & dosage</subject><subject>Chlorhexidine - therapeutic use</subject><subject>Dental Service, Hospital</subject><subject>Dentistry</subject><subject>Diphosphonates - administration & dosage</subject><subject>Diphosphonates - adverse effects</subject><subject>Diseases of the osteoarticular system</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Jaw Diseases - chemically induced</subject><subject>Jaw Diseases - psychology</subject><subject>Jaw Diseases - therapy</subject><subject>Mass Screening</subject><subject>Medical sciences</subject><subject>Molar - surgery</subject><subject>Osteonecrosis - chemically induced</subject><subject>Osteonecrosis - psychology</subject><subject>Osteonecrosis - therapy</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Pharmacology. Drug treatments</subject><subject>Practice Patterns, Dentists</subject><subject>Societies, Dental</subject><subject>Surgery</subject><subject>Surgery, Oral</subject><subject>Survey</subject><subject>Surveys and Questionnaires</subject><subject>Time Factors</subject><subject>Tooth Extraction</subject><subject>Tooth Socket - physiology</subject><subject>United Kingdom</subject><subject>Vascular bone diseases</subject><subject>Wound Healing - physiology</subject><issn>0266-4356</issn><issn>1532-1940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkstu1DAUhiMEotPCEyAhbxCrDMd2rguQphUFpKIuCmvLcU5mHBJ78EkK8yS8Lg4zKhIbLFmWfL5z8f87SV5wWHPgxZt-3fR-pLUAqNdQrkHAo2TFcylSXmfwOFmBKIo0k3lxlpwT9QCQC54_Tc54XWZVyfkq-bVhNId7PDDfMeMdzcOk3cRGHBsMtNxOO2SXwU6WdmxD5I3Vk_VuCd0GPTDtWvZZ_7TD4DsdgwO7m8MWYy0WcKtDa92WNZb2O79spydMrWtngy3zNEUQTfBkH5r1-gc9S550eiB8fjovkq_X779cfUxvbj98utrcpCYr6inlpmtyrHNRtK3JoOZ1VQldNHnWYCYrzbXRBUgjikrmbV2VedN1RnYoKp7pMpMXyetj3X3w32ekSY2WDA6DduhnUqWUBUAp6kjKI7kMSwE7tQ921OGgOKjFENWrP4aoxRAFpYqGxKyXp_pzM2L7N-fkQARenQBNRg9d0M5YeuBEXFl8VOTeHjmMatxbDIqMRRdFtAHNpFpv_zPIu3_yzWCdjS2_4QGp93NwUWjFFQkF6m75O8vXgRogi-LJ3-9ewnY</recordid><startdate>20091201</startdate><enddate>20091201</enddate><creator>Rogers, S.N</creator><creator>Hung, J</creator><creator>Barber, A.J</creator><creator>Lowe, D</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20091201</creationdate><title>A survey of consultant members of the British Association of Oral and Maxillofacial Surgeons regarding bisphosphonate-induced osteonecrosis of the jaws</title><author>Rogers, S.N ; Hung, J ; Barber, A.J ; Lowe, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c469t-1cfb5e9526ddc40919882a6b54be438a1aca603c26835d9875bffc3fe2814a743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Administration, Oral</topic><topic>Anti-Infective Agents, Local - administration & dosage</topic><topic>Anti-Infective Agents, Local - therapeutic use</topic><topic>Antibiotic Prophylaxis</topic><topic>Attitude of Health Personnel</topic><topic>Biological and medical sciences</topic><topic>Bisphosphonate-induced osteonecrosis of the jaws</topic><topic>Bisphosphonates</topic><topic>Bone Density Conservation Agents - administration & dosage</topic><topic>Bone Density Conservation Agents - adverse effects</topic><topic>Bones, joints and connective tissue. Antiinflammatory agents</topic><topic>British Association of Oral and Maxillofacial Surgeons</topic><topic>Chlorhexidine - administration & dosage</topic><topic>Chlorhexidine - therapeutic use</topic><topic>Dental Service, Hospital</topic><topic>Dentistry</topic><topic>Diphosphonates - administration & dosage</topic><topic>Diphosphonates - adverse effects</topic><topic>Diseases of the osteoarticular system</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Jaw Diseases - chemically induced</topic><topic>Jaw Diseases - psychology</topic><topic>Jaw Diseases - therapy</topic><topic>Mass Screening</topic><topic>Medical sciences</topic><topic>Molar - surgery</topic><topic>Osteonecrosis - chemically induced</topic><topic>Osteonecrosis - psychology</topic><topic>Osteonecrosis - therapy</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Pharmacology. 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Nearly two-thirds of consultants had seen new cases of BONJ from intravenous treatment in the last year, and a quarter had seen three or more. A similar proportion had patients on intravenous bisphosphonates under review for BONJ, and it was estimated that in a fifth of patients the lesion had healed. This survey indicates current practice among oral and maxillofacial surgeons in the UK. A national project for the registration of new patients will provide a stronger evidence base with respect to incidence, risk factors, and management of BONJ.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>19748711</pmid><doi>10.1016/j.bjoms.2009.07.020</doi><tpages>4</tpages></addata></record> |
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subjects | Administration, Oral Anti-Infective Agents, Local - administration & dosage Anti-Infective Agents, Local - therapeutic use Antibiotic Prophylaxis Attitude of Health Personnel Biological and medical sciences Bisphosphonate-induced osteonecrosis of the jaws Bisphosphonates Bone Density Conservation Agents - administration & dosage Bone Density Conservation Agents - adverse effects Bones, joints and connective tissue. Antiinflammatory agents British Association of Oral and Maxillofacial Surgeons Chlorhexidine - administration & dosage Chlorhexidine - therapeutic use Dental Service, Hospital Dentistry Diphosphonates - administration & dosage Diphosphonates - adverse effects Diseases of the osteoarticular system Humans Injections, Intravenous Jaw Diseases - chemically induced Jaw Diseases - psychology Jaw Diseases - therapy Mass Screening Medical sciences Molar - surgery Osteonecrosis - chemically induced Osteonecrosis - psychology Osteonecrosis - therapy Otorhinolaryngology. Stomatology Pharmacology. Drug treatments Practice Patterns, Dentists Societies, Dental Surgery Surgery, Oral Survey Surveys and Questionnaires Time Factors Tooth Extraction Tooth Socket - physiology United Kingdom Vascular bone diseases Wound Healing - physiology |
title | A survey of consultant members of the British Association of Oral and Maxillofacial Surgeons regarding bisphosphonate-induced osteonecrosis of the jaws |
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