Role of fibrinogen in trauma-induced coagulopathy

Coagulation defects related to severe trauma, trauma-induced coagulopathy (TIC), have a number of causal factors including: major blood loss with consumption of clotting factors and platelets, and dilutional coagulopathy after administration of crystalloids and colloids to maintain blood pressure. I...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2010-08, Vol.105 (2), p.116-121
Hauptverfasser:	Fries, D, Martini, W.Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis - blood Acidosis - etiology Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Coagulation Disorders - blood Blood Coagulation Disorders - drug therapy Blood Coagulation Disorders - etiology Blood Platelets - metabolism Coagulants - therapeutic use coagulation Fibrinogen - metabolism Fibrinogen - therapeutic use Fibrinolysis Fluid Therapy - methods Humans Hypothermia - blood Medical sciences transfusion trauma Wounds and Injuries - complications
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