New strategies for craniofacial repair and replacement: a brief review
Craniofacial anomalies can severely affect the appearance, function, and psychosocial well being of patients; thus, tissue engineers are developing new techniques to functionally and aesthetically rebuild craniofacial structures. In the past decade, there have been tremendous advances in the field o...
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| Veröffentlicht in: | The Journal of craniofacial surgery 2003-05, Vol.14 (3), p.333-339 |
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| container_title | The Journal of craniofacial surgery |
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| creator | Fong, Kenton D Nacamuli, Randall P Song, HanJoon M Warren, Stephen M Lorenz, H Peter Longaker, Michael T |
| description | Craniofacial anomalies can severely affect the appearance, function, and psychosocial well being of patients; thus, tissue engineers are developing new techniques to functionally and aesthetically rebuild craniofacial structures. In the past decade, there have been tremendous advances in the field of tissue engineering that will substantially alter how surgeons approach craniofacial reconstruction. In this brief review, we highlight some of the preclinical recombinant protein, gene transfer, and cell-based strategies currently being developed to augment endogenous tissue repair or create structures for replacement. In addition, we discuss the importance of studying endogenous models of tissue induction and present some of the current in vitro and in vivo approaches to growing complex tissues/organs for craniofacial reconstruction. |
| doi_str_mv | 10.1097/00001665-200305000-00011 |
| format | Article |
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| ispartof | The Journal of craniofacial surgery, 2003-05, Vol.14 (3), p.333-339 |
| issn | 1049-2275 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Animals Cell Transplantation Cells, Cultured - transplantation Craniofacial Abnormalities - therapy Dentistry Genetic Therapy - methods Genetic Vectors - therapeutic use Humans Models, Biological Prostheses and Implants Recombinant Proteins - therapeutic use Reconstructive Surgical Procedures - methods Regeneration Tissue Engineering - methods |
| title | New strategies for craniofacial repair and replacement: a brief review |
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