Regulation of the expression of inducible nitric oxide synthase

Nitric oxide (NO) generated by the inducible isoform of nitric oxide synthase (iNOS) is involved in complex immunomodulatory and antitumoral mechanisms and has been described to have multiple beneficial microbicidal, antiviral and antiparasital effects. However, dysfunctional induction of iNOS expre...

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Veröffentlicht in:	Nitric oxide 2010-09, Vol.23 (2), p.75-93
Hauptverfasser:	Pautz, Andrea, Art, Julia, Hahn, Susanne, Nowag, Sebastian, Voss, Cornelia, Kleinert, Hartmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Expression Gene Expression Regulation, Enzymologic Humans iNOS mRNA stability Nitric Oxide Synthase Type II - biosynthesis Nitric Oxide Synthase Type II - genetics Promoter Promoter Regions, Genetic - genetics RNA, Messenger - genetics RNA, Messenger - metabolism RNA-binding proteins RNA-Binding Proteins - metabolism Transcription factors Transcription Factors - metabolism
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