Ectopic opening of the common bile duct into various sites of the upper digestive tract: a case series

Background Ectopic opening of the common bile duct (CBD) into the GI tract is an extremely rare congenital anomaly. The clinical implications and frequency of this anomaly are not clearly known. Objective To present a case series of ectopic opening of the CBD into various sites of the upper digestiv...

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Veröffentlicht in:Gastrointestinal endoscopy 2010-07, Vol.72 (1), p.198-203
Hauptverfasser: Sezgin, Orhan, MD, Altintaş, Engin, MD, Üçbilek, Enver, MD
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creator Sezgin, Orhan, MD
Altintaş, Engin, MD
Üçbilek, Enver, MD
description Background Ectopic opening of the common bile duct (CBD) into the GI tract is an extremely rare congenital anomaly. The clinical implications and frequency of this anomaly are not clearly known. Objective To present a case series of ectopic opening of the CBD into various sites of the upper digestive tract and discuss clinicopathological features of this condition. Design and Setting Retrospective, observational study in a single tertiary care medical center. Patients Consecutive patients undergoing ERCP who received a diagnosis of an ectopic opening of the CBD between September 2001 and August 2009 were reviewed. Interventions Endoscopic and cholangiographic findings were reviewed. Main Outcome Measurements The endoscopic and cholangiographic findings and clinical course of these patients were reviewed. Results During the study period, 1040 patients underwent ERCP. A total of 11 patients (6 men and 5 women with a median age of 59.2 years) received a diagnosis of an ectopic opening of the CBD. The opening sites of the CBD were located as follow: 1 in the stomach, 4 in the duodenal bulb, 3 at a more lateral site of the second portion of the duodenum, and 3 in the third part of the duodenum. Seven patients had choledocholithiasis, 2 had acute pancreatitis, and 3 had severe cholangitis. Conclusion Although an ectopic opening of the CBD is rare, it may be associated with severe pancreaticobiliary disorders. Endoscopists should be aware of this anomaly and know what to do in case they encounter the condition.
doi_str_mv 10.1016/j.gie.2010.02.012
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The clinical implications and frequency of this anomaly are not clearly known. Objective To present a case series of ectopic opening of the CBD into various sites of the upper digestive tract and discuss clinicopathological features of this condition. Design and Setting Retrospective, observational study in a single tertiary care medical center. Patients Consecutive patients undergoing ERCP who received a diagnosis of an ectopic opening of the CBD between September 2001 and August 2009 were reviewed. Interventions Endoscopic and cholangiographic findings were reviewed. Main Outcome Measurements The endoscopic and cholangiographic findings and clinical course of these patients were reviewed. Results During the study period, 1040 patients underwent ERCP. A total of 11 patients (6 men and 5 women with a median age of 59.2 years) received a diagnosis of an ectopic opening of the CBD. The opening sites of the CBD were located as follow: 1 in the stomach, 4 in the duodenal bulb, 3 at a more lateral site of the second portion of the duodenum, and 3 in the third part of the duodenum. Seven patients had choledocholithiasis, 2 had acute pancreatitis, and 3 had severe cholangitis. Conclusion Although an ectopic opening of the CBD is rare, it may be associated with severe pancreaticobiliary disorders. Endoscopists should be aware of this anomaly and know what to do in case they encounter the condition.</description><identifier>ISSN: 0016-5107</identifier><identifier>EISSN: 1097-6779</identifier><identifier>DOI: 10.1016/j.gie.2010.02.012</identifier><identifier>PMID: 20493479</identifier><identifier>CODEN: GAENBQ</identifier><language>eng</language><publisher>Maryland heights, MO: Mosby, Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Cholangiopancreatography, Endoscopic Retrograde ; Cholangitis - diagnosis ; Cholangitis - therapy ; Common Bile Duct - abnormalities ; Digestive System Abnormalities - diagnosis ; Digestive System Abnormalities - therapy ; Digestive system. Abdomen ; Duodenum - abnormalities ; Endoscopy ; Female ; Gallstones - diagnosis ; Gallstones - therapy ; Gastroenterology and Hepatology ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Jaundice, Obstructive - diagnosis ; Jaundice, Obstructive - therapy ; Male ; Medical sciences ; Middle Aged ; Pancreatitis, Acute Necrotizing - diagnosis ; Pancreatitis, Acute Necrotizing - therapy ; Retrospective Studies ; Sensitivity and Specificity ; Stomach - abnormalities ; Ultrasonography</subject><ispartof>Gastrointestinal endoscopy, 2010-07, Vol.72 (1), p.198-203</ispartof><rights>American Society for Gastrointestinal Endoscopy</rights><rights>2010 American Society for Gastrointestinal Endoscopy</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. 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The clinical implications and frequency of this anomaly are not clearly known. Objective To present a case series of ectopic opening of the CBD into various sites of the upper digestive tract and discuss clinicopathological features of this condition. Design and Setting Retrospective, observational study in a single tertiary care medical center. Patients Consecutive patients undergoing ERCP who received a diagnosis of an ectopic opening of the CBD between September 2001 and August 2009 were reviewed. Interventions Endoscopic and cholangiographic findings were reviewed. Main Outcome Measurements The endoscopic and cholangiographic findings and clinical course of these patients were reviewed. Results During the study period, 1040 patients underwent ERCP. A total of 11 patients (6 men and 5 women with a median age of 59.2 years) received a diagnosis of an ectopic opening of the CBD. The opening sites of the CBD were located as follow: 1 in the stomach, 4 in the duodenal bulb, 3 at a more lateral site of the second portion of the duodenum, and 3 in the third part of the duodenum. Seven patients had choledocholithiasis, 2 had acute pancreatitis, and 3 had severe cholangitis. Conclusion Although an ectopic opening of the CBD is rare, it may be associated with severe pancreaticobiliary disorders. Endoscopists should be aware of this anomaly and know what to do in case they encounter the condition.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Cholangiopancreatography, Endoscopic Retrograde</subject><subject>Cholangitis - diagnosis</subject><subject>Cholangitis - therapy</subject><subject>Common Bile Duct - abnormalities</subject><subject>Digestive System Abnormalities - diagnosis</subject><subject>Digestive System Abnormalities - therapy</subject><subject>Digestive system. Abdomen</subject><subject>Duodenum - abnormalities</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Gallstones - diagnosis</subject><subject>Gallstones - therapy</subject><subject>Gastroenterology and Hepatology</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Jaundice, Obstructive - diagnosis</subject><subject>Jaundice, Obstructive - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pancreatitis, Acute Necrotizing - diagnosis</subject><subject>Pancreatitis, Acute Necrotizing - therapy</subject><subject>Retrospective Studies</subject><subject>Sensitivity and Specificity</subject><subject>Stomach - abnormalities</subject><subject>Ultrasonography</subject><issn>0016-5107</issn><issn>1097-6779</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks9rFDEUx4Modl39A7xILuJp1vyapKMgSKmtUPDQeg6ZzJv1rTOTMcks9L83y24reOgpJPl833t8eIS85WzDGdcfd5stwkawcmdiw7h4RlacNabSxjTPyYoVqKo5M2fkVUo7xti5kPwlORNMNVKZZkX6S5_DjJ6GGSactjT0NP8C6sM4hom2OADtFp8pTjnQvYsYlkQTZkgP6DLPEGmHW0gZ90BzdD5_oo56l4AmiAjpNXnRuyHBm9O5Jj-_Xd5dXFc3P66-X3y9qbySJlei1rKXfStYp3XNfd-CEsp0vPGyPIJpQTBdPqXx2tRGSaiV0lKDrs-7upVr8uFYd47hz1IGsiMmD8PgJiiDWyNl3SgpeSH5kfQxpBSht3PE0cV7y5k92LU7W-zag13LhC12S-bdqfrSjtA9Jh50FuD9CXDJu6GPbvKY_nGiaYwu_dfk85GD4mKPEG3yCJOHDiP4bLuAT47x5b-0H3DC0vA33EPahSVORbLlNpWAvT2swWELeFkAXmsh_wIFK6tL</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>Sezgin, Orhan, MD</creator><creator>Altintaş, Engin, MD</creator><creator>Üçbilek, Enver, MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100701</creationdate><title>Ectopic opening of the common bile duct into various sites of the upper digestive tract: a case series</title><author>Sezgin, Orhan, MD ; Altintaş, Engin, MD ; Üçbilek, Enver, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c437t-2563f3fb20d6651cfbe4247d19c3b20e7be2060d637c675743e544636e658d5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Cholangiopancreatography, Endoscopic Retrograde</topic><topic>Cholangitis - diagnosis</topic><topic>Cholangitis - therapy</topic><topic>Common Bile Duct - abnormalities</topic><topic>Digestive System Abnormalities - diagnosis</topic><topic>Digestive System Abnormalities - therapy</topic><topic>Digestive system. Abdomen</topic><topic>Duodenum - abnormalities</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Gallstones - diagnosis</topic><topic>Gallstones - therapy</topic><topic>Gastroenterology and Hepatology</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Jaundice, Obstructive - diagnosis</topic><topic>Jaundice, Obstructive - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pancreatitis, Acute Necrotizing - diagnosis</topic><topic>Pancreatitis, Acute Necrotizing - therapy</topic><topic>Retrospective Studies</topic><topic>Sensitivity and Specificity</topic><topic>Stomach - abnormalities</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sezgin, Orhan, MD</creatorcontrib><creatorcontrib>Altintaş, Engin, MD</creatorcontrib><creatorcontrib>Üçbilek, Enver, MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gastrointestinal endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sezgin, Orhan, MD</au><au>Altintaş, Engin, MD</au><au>Üçbilek, Enver, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ectopic opening of the common bile duct into various sites of the upper digestive tract: a case series</atitle><jtitle>Gastrointestinal endoscopy</jtitle><addtitle>Gastrointest Endosc</addtitle><date>2010-07-01</date><risdate>2010</risdate><volume>72</volume><issue>1</issue><spage>198</spage><epage>203</epage><pages>198-203</pages><issn>0016-5107</issn><eissn>1097-6779</eissn><coden>GAENBQ</coden><abstract>Background Ectopic opening of the common bile duct (CBD) into the GI tract is an extremely rare congenital anomaly. The clinical implications and frequency of this anomaly are not clearly known. Objective To present a case series of ectopic opening of the CBD into various sites of the upper digestive tract and discuss clinicopathological features of this condition. Design and Setting Retrospective, observational study in a single tertiary care medical center. Patients Consecutive patients undergoing ERCP who received a diagnosis of an ectopic opening of the CBD between September 2001 and August 2009 were reviewed. Interventions Endoscopic and cholangiographic findings were reviewed. Main Outcome Measurements The endoscopic and cholangiographic findings and clinical course of these patients were reviewed. Results During the study period, 1040 patients underwent ERCP. A total of 11 patients (6 men and 5 women with a median age of 59.2 years) received a diagnosis of an ectopic opening of the CBD. The opening sites of the CBD were located as follow: 1 in the stomach, 4 in the duodenal bulb, 3 at a more lateral site of the second portion of the duodenum, and 3 in the third part of the duodenum. Seven patients had choledocholithiasis, 2 had acute pancreatitis, and 3 had severe cholangitis. Conclusion Although an ectopic opening of the CBD is rare, it may be associated with severe pancreaticobiliary disorders. Endoscopists should be aware of this anomaly and know what to do in case they encounter the condition.</abstract><cop>Maryland heights, MO</cop><pub>Mosby, Inc</pub><pmid>20493479</pmid><doi>10.1016/j.gie.2010.02.012</doi><tpages>6</tpages></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Biological and medical sciences
Cholangiopancreatography, Endoscopic Retrograde
Cholangitis - diagnosis
Cholangitis - therapy
Common Bile Duct - abnormalities
Digestive System Abnormalities - diagnosis
Digestive System Abnormalities - therapy
Digestive system. Abdomen
Duodenum - abnormalities
Endoscopy
Female
Gallstones - diagnosis
Gallstones - therapy
Gastroenterology and Hepatology
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Investigative techniques, diagnostic techniques (general aspects)
Jaundice, Obstructive - diagnosis
Jaundice, Obstructive - therapy
Male
Medical sciences
Middle Aged
Pancreatitis, Acute Necrotizing - diagnosis
Pancreatitis, Acute Necrotizing - therapy
Retrospective Studies
Sensitivity and Specificity
Stomach - abnormalities
Ultrasonography
title Ectopic opening of the common bile duct into various sites of the upper digestive tract: a case series
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