A comparative study of chitosan and chitosan/cyclodextrin nanoparticles as potential carriers for the oral delivery of small peptides

The aim of this study was to characterize new nanoparticles (NPs) containing chitosan (CS), or CS/cyclodextrin (CDs), and evaluate their potential for the oral delivery of the peptide glutathione (GSH). More precisely, NP formulations composed of CS, CS/α-CD and CS/sulphobutyl ether-β-cyclodextrin (...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2010-05, Vol.75 (1), p.26-32
Hauptverfasser:	Trapani, Adriana, Lopedota, Angela, Franco, Massimo, Cioffi, Nicola, Ieva, Eliana, Garcia-Fuentes, Marcos, Alonso, Maria José
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Chitosan Cyclodextrins Cyclodextrins - administration & dosage Cyclodextrins - pharmacokinetics Drug Carriers - administration & dosage Drug Carriers - pharmacokinetics Drug Delivery Systems - methods General pharmacology Glutathione Glutathione - administration & dosage Glutathione - pharmacokinetics Intestinal Absorption - drug effects Intestinal Absorption - physiology Medical sciences Nanoparticles Nanoparticles - administration & dosage Oral administration Peptide Fragments - administration & dosage Peptide Fragments - pharmacokinetics Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rana esculenta
Online-Zugang:	Volltext
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