Influence of number of calibration standards within a defined range on pharmacokinetic disposition-case studies with omeprazole and clopidogrel carboxylic acid

While the practice of using a smaller number of non‐zero standards (typically seven to eight) has not been entertained in routine bioanalytical work, it is important to innovate and be pragmatic about minimizing the number of calibration standards to promote cost‐effective and speedy assessment. In...

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Veröffentlicht in:	Biomedical chromatography 2010-05, Vol.24 (5), p.544-549
Hauptverfasser:	D'Souza, Henry John Baptist, Pai, Balakrishna, Kumar, Anil, Shekar, Radha, Srinivas, Nuggehally R., Kristjansson, Fjalar
Format:	Artikel
Sprache:	eng
Schlagworte:	Calibration - standards calibration curve Chromatography, Liquid - methods Chromatography, Liquid - standards clopidogrel carboxylic acid Humans Mass Spectrometry - methods Mass Spectrometry - standards omeprazole Omeprazole - blood pharmacokinetics Reference Standards regression Ticlopidine - analogs & derivatives Ticlopidine - blood
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