Inflammatory Monocytes Are a Reservoir for Merkel Cell Polyomavirus

Merkel cell polyomavirus (MCPyV) is a recently discovered virus that is implicated in the oncogenesis of Merkel cell carcinoma (MCC). The route of dissemination and the reservoir(s) of MCPyV within the human body have not yet been identified. In this study we describe two patients with multiple MCPy...

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Veröffentlicht in:	Journal of investigative dermatology 2010-04, Vol.130 (4), p.1146-1151
Hauptverfasser:	Mertz, Kirsten D., Junt, Tobias, Schmid, Mirka, Pfaltz, Madeleine, Kempf, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Carcinoma, Merkel Cell - immunology Carcinoma, Merkel Cell - pathology Carcinoma, Merkel Cell - virology Dermatology Female Humans Immunocompromised Host Infectious diseases Kidney Transplantation Male Medical sciences Middle Aged Monocytes - virology Polyomavirus - genetics Polyomavirus - isolation & purification Polyomavirus Infections - complications Polyomavirus Infections - immunology Polyomavirus Infections - pathology Psoriasis - complications Skin Neoplasms - immunology Skin Neoplasms - pathology Skin Neoplasms - virology Viral diseases
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