A nano-Ni based ultrasensitive nonenzymatic electrochemical sensor for glucose: Enhancing sensitivity through a nanowire array strategy

Highly ordered Ni nanowire arrays (NiNWAs) were synthesized for the first time using a template-directed electropolymerization strategy with a nanopore polycarbonate (PC) membrane template, and their morphological characterization were examined by scanning electron microscopy (SEM) and transmission...

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Veröffentlicht in:Biosensors & bioelectronics 2009-09, Vol.25 (1), p.218-223
Hauptverfasser: Lu, Li-Min, Zhang, Li, Qu, Feng-Li, Lu, Hai-Xia, Zhang, Xiao-Bing, Wu, Zai-Sheng, Huan, Shuang-Yan, Wang, Qiu-An, Shen, Guo-Li, Yu, Ru-Qin
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container_issue 1
container_start_page 218
container_title Biosensors & bioelectronics
container_volume 25
creator Lu, Li-Min
Zhang, Li
Qu, Feng-Li
Lu, Hai-Xia
Zhang, Xiao-Bing
Wu, Zai-Sheng
Huan, Shuang-Yan
Wang, Qiu-An
Shen, Guo-Li
Yu, Ru-Qin
description Highly ordered Ni nanowire arrays (NiNWAs) were synthesized for the first time using a template-directed electropolymerization strategy with a nanopore polycarbonate (PC) membrane template, and their morphological characterization were examined by scanning electron microscopy (SEM) and transmission electron microscope (TEM). A NiNWAs based electrode shows very high electrochemical activity for electrocatalytic oxidation of glucose in alkaline medium, which has been utilized as the basis of the fabrication of a nonenzymatic biosensor for electrochemical detection of glucose. The biosensor can be applied to the quantification of glucose with a linear range covering from 5.0 × 10 −7 to 7.0 × 10 −3 M, a high sensitivity of 1043 μA mM −1 cm −2, and a low detection limit of 1 × 10 −7 M. The experiment results also showed that the sensor exhibits good reproducibility and long-term stability, as well as high selectivity with no interference from other oxidable species.
doi_str_mv 10.1016/j.bios.2009.06.041
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Amperometry
Arrays
Biological and medical sciences
Biosensing Techniques - methods
Biosensors
Biotechnology
Electrochemistry - methods
Electrodes
Electropolymerization
Fundamental and applied biological sciences. Psychology
Glucose
Glucose - analysis
Nanocomposites
Nanomaterials
Nanowires
Nanowires - chemistry
Nanowires - ultrastructure
Ni nanowire arrays
Nickel - chemistry
Nonenzymatic sensor
Oxidation-Reduction
Scanning electron microscopy
Sensitivity and Specificity
Strategy
title A nano-Ni based ultrasensitive nonenzymatic electrochemical sensor for glucose: Enhancing sensitivity through a nanowire array strategy
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