Clinical trial: a randomized trial of pegylated-interferon-alpha-2a plus ribavirin with or without amantadine in treatment-naïve or relapsing chronic hepatitis C patients

The combination therapy of pegylated-interferon-alpha2a plus ribavirin is considered as the standard of care for patients with chronic hepatitis C. A sustained viral response is obtained in 40-50% of naïve patients with genotype 1 and in around 80% of naïve patients with genotype 2 or 3. To assess w...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2009-08, Vol.30 (4), p.352-363
Hauptverfasser:	Langlet, P, D'Heygere, F, Henrion, J, Adler, M, Delwaide, J, Van Vlierberghe, H, Mulkay, J P, Lasser, L, Brenard, R, Horsmans, Y, Michielsen, P, Laureys, A, Nevens, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Amantadine - administration & dosage Antiviral Agents - administration & dosage Drug Therapy, Combination Female Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology Humans Interferon-alpha - administration & dosage Male Middle Aged Polyethylene Glycols - administration & dosage Recombinant Proteins Regression Analysis Ribavirin - administration & dosage Treatment Outcome Young Adult
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