Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

The mechanisms of peroxisomal biogenesis remain incompletely understood, specially regarding the role of the endoplasmic reticulum (ER) in human cells, where genetic disorders of peroxisome biogenesis lead to Zellweger syndrome (ZS). The Pex3p peroxisomal membrane protein (PMP) required for early st...

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Veröffentlicht in:	Journal of cellular biochemistry 2009-08, Vol.107 (6), p.1083-1096
Hauptverfasser:	Toro, Andrés A., Araya, Claudia A., Córdova, Gonzalo J., Arredondo, Cristian A., Cárdenas, Hugo G., Moreno, Regina E., Venegas, Alejandro, Koenig, Cecilia S., Cancino, Jorge, Gonzalez, Alfonso, Santos, Manuel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyltransferases biogenesis Case-Control Studies Catalase endoplasmic reticulum Endoplasmic Reticulum - enzymology Endoplasmic Reticulum - metabolism Fibroblasts - cytology Humans Lipoproteins - genetics Lipoproteins - metabolism Lipoproteins - physiology Membrane Proteins - genetics Membrane Proteins - metabolism Membrane Proteins - physiology Mutation Peroxins peroxisome Peroxisomes - metabolism Protein Transport Zellweger Syndrome
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