Local anaesthesia for manipulation of nasal fractures: systematic review

To determine the most effective local anaesthetic method for manipulation of nasal fractures, and to compare the efficacy of local anaesthesia with that of general anaesthesia. Systematic review and meta-analysis. Medline, Embase, Cochrane Library, National Research Register and metaRegister of Cont...

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Veröffentlicht in:Journal of laryngology and otology 2009-08, Vol.123 (8), p.830-836
Hauptverfasser: Chadha, N K, Repanos, C, Carswell, A J
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container_title Journal of laryngology and otology
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creator Chadha, N K
Repanos, C
Carswell, A J
description To determine the most effective local anaesthetic method for manipulation of nasal fractures, and to compare the efficacy of local anaesthesia with that of general anaesthesia. Systematic review and meta-analysis. Medline, Embase, Cochrane Library, National Research Register and metaRegister of Controlled Trials. We included randomised, controlled trials comparing general anaesthesia with local anaesthesia or comparing different local anaesthetic techniques. Non-randomised studies were also systematically reviewed and appraised. No language restrictions were applied. Five randomised, controlled trials were included, three comparing general anaesthesia versus local anaesthesia and two comparing different local anaesthetic methods. No significant differences were found between local anaesthesia and general anaesthesia as regards pain, cosmesis or nasal patency. The least painful local anaesthetic method was topical tetracaine gel applied to the nasal dorsum together with topical intranasal cocaine solution. Minimal adverse events were reported with local anaesthesia. Local anaesthesia appears to be a safe and effective alternative to general anaesthesia for pain relief during nasal fracture manipulation, with no evidence of inferior outcomes. The least uncomfortable local anaesthetic method included topical tetracaine gel.
doi_str_mv 10.1017/S002221510900560X
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Systematic review and meta-analysis. Medline, Embase, Cochrane Library, National Research Register and metaRegister of Controlled Trials. We included randomised, controlled trials comparing general anaesthesia with local anaesthesia or comparing different local anaesthetic techniques. Non-randomised studies were also systematically reviewed and appraised. No language restrictions were applied. Five randomised, controlled trials were included, three comparing general anaesthesia versus local anaesthesia and two comparing different local anaesthetic methods. No significant differences were found between local anaesthesia and general anaesthesia as regards pain, cosmesis or nasal patency. The least painful local anaesthetic method was topical tetracaine gel applied to the nasal dorsum together with topical intranasal cocaine solution. Minimal adverse events were reported with local anaesthesia. 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Injuries of the spine ; Local ; Local anesthesia ; Manipulation ; Manipulation, Orthopedic - methods ; Medical sciences ; Nasal Bone - injuries ; Nasal Bones ; Nasal Obstruction ; Nasal Obstruction - therapy ; Non tumoral diseases ; Nose ; Otorhinolaryngology (head neck, general aspects and miscellaneous) ; Otorhinolaryngology. Stomatology ; Pain ; Pain - prevention &amp; control ; Patients ; Randomized Controlled Trials as Topic ; Surgeons ; Systematic Review ; Trauma ; Traumas. 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Laryngol. Otol</addtitle><description>To determine the most effective local anaesthetic method for manipulation of nasal fractures, and to compare the efficacy of local anaesthesia with that of general anaesthesia. Systematic review and meta-analysis. Medline, Embase, Cochrane Library, National Research Register and metaRegister of Controlled Trials. We included randomised, controlled trials comparing general anaesthesia with local anaesthesia or comparing different local anaesthetic techniques. Non-randomised studies were also systematically reviewed and appraised. No language restrictions were applied. Five randomised, controlled trials were included, three comparing general anaesthesia versus local anaesthesia and two comparing different local anaesthetic methods. No significant differences were found between local anaesthesia and general anaesthesia as regards pain, cosmesis or nasal patency. 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Injuries of the spine</subject><subject>Local</subject><subject>Local anesthesia</subject><subject>Manipulation</subject><subject>Manipulation, Orthopedic - methods</subject><subject>Medical sciences</subject><subject>Nasal Bone - injuries</subject><subject>Nasal Bones</subject><subject>Nasal Obstruction</subject><subject>Nasal Obstruction - therapy</subject><subject>Non tumoral diseases</subject><subject>Nose</subject><subject>Otorhinolaryngology (head neck, general aspects and miscellaneous)</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Pain</subject><subject>Pain - prevention &amp; control</subject><subject>Patients</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Surgeons</subject><subject>Systematic Review</subject><subject>Trauma</subject><subject>Traumas. 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Injuries of the spine</topic><topic>Local</topic><topic>Local anesthesia</topic><topic>Manipulation</topic><topic>Manipulation, Orthopedic - methods</topic><topic>Medical sciences</topic><topic>Nasal Bone - injuries</topic><topic>Nasal Bones</topic><topic>Nasal Obstruction</topic><topic>Nasal Obstruction - therapy</topic><topic>Non tumoral diseases</topic><topic>Nose</topic><topic>Otorhinolaryngology (head neck, general aspects and miscellaneous)</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Pain</topic><topic>Pain - prevention &amp; control</topic><topic>Patients</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Surgeons</topic><topic>Systematic Review</topic><topic>Trauma</topic><topic>Traumas. 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Laryngol. Otol</addtitle><date>2009-08-01</date><risdate>2009</risdate><volume>123</volume><issue>8</issue><spage>830</spage><epage>836</epage><pages>830-836</pages><issn>0022-2151</issn><eissn>1748-5460</eissn><coden>JLOTAX</coden><abstract>To determine the most effective local anaesthetic method for manipulation of nasal fractures, and to compare the efficacy of local anaesthesia with that of general anaesthesia. Systematic review and meta-analysis. Medline, Embase, Cochrane Library, National Research Register and metaRegister of Controlled Trials. We included randomised, controlled trials comparing general anaesthesia with local anaesthesia or comparing different local anaesthetic techniques. Non-randomised studies were also systematically reviewed and appraised. No language restrictions were applied. Five randomised, controlled trials were included, three comparing general anaesthesia versus local anaesthesia and two comparing different local anaesthetic methods. No significant differences were found between local anaesthesia and general anaesthesia as regards pain, cosmesis or nasal patency. The least painful local anaesthetic method was topical tetracaine gel applied to the nasal dorsum together with topical intranasal cocaine solution. Minimal adverse events were reported with local anaesthesia. Local anaesthesia appears to be a safe and effective alternative to general anaesthesia for pain relief during nasal fracture manipulation, with no evidence of inferior outcomes. The least uncomfortable local anaesthetic method included topical tetracaine gel.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>19470190</pmid><doi>10.1017/S002221510900560X</doi><tpages>7</tpages></addata></record>
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subjects Anaesthesia
Anesthesia, General - methods
Anesthesia, Local - methods
Biological and medical sciences
Cosmetic
Fractures
Fractures, Bone - surgery
General anesthesia
Humans
Injuries of the limb. Injuries of the spine
Local
Local anesthesia
Manipulation
Manipulation, Orthopedic - methods
Medical sciences
Nasal Bone - injuries
Nasal Bones
Nasal Obstruction
Nasal Obstruction - therapy
Non tumoral diseases
Nose
Otorhinolaryngology (head neck, general aspects and miscellaneous)
Otorhinolaryngology. Stomatology
Pain
Pain - prevention & control
Patients
Randomized Controlled Trials as Topic
Surgeons
Systematic Review
Trauma
Traumas. Diseases due to physical agents
title Local anaesthesia for manipulation of nasal fractures: systematic review
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