Hexarelin suppresses high lipid diet and vitamin D3-induced atherosclerosis in the rat

Growth hormone-releasing peptides (GHRP) and ghrelin are synthetic and natural ligands of growth hormone secretagogue receptor (GHSR) respectively and are shown to exert protective actions on cardiac dysfunction. Because ghrelin has been reported to inhibit proinflammatory responses in human endothe...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2010-04, Vol.31 (4), p.630-638
Hauptverfasser:	JINJIANG PANG, QIHUA XU, XIANGBIN XU, HONGCHAO YIN, RONGKUN XU, SHU GUO, WEI HAO, LUYA WANG, CHEN CHEN, CAO, Ji-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - metabolism Aorta - pathology Atherosclerosis (general aspects, experimental research) Atherosclerosis - chemically induced Atherosclerosis - drug therapy Atherosclerosis - pathology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cholecalciferol - pharmacology Dietary Fats - adverse effects Female Fundamental and applied biological sciences. Psychology Ghrelin - metabolism Humans Lipoproteins - blood Male Medical sciences Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - drug effects Nitric Oxide - metabolism Nitric Oxide Synthase Type III - genetics Nitric Oxide Synthase Type III - metabolism Oligopeptides - therapeutic use Random Allocation Rats Rats, Sprague-Dawley Vertebrates: endocrinology
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