In Vitro Photodynamic Activity of 5,15-bis(3-Hydroxyphenyl)porphyrin and Its Halogenated Derivatives Against Cancer Cells

5,15‐Diarylporphyrins (1‐5) with hydroxyl groups and halogens as substituents were prepared by condensation between unsubstituted dipyrromethane and halogenated m‐hydroxybenzaldehydes. Photophysical properties show that the nonhalogenated porphyrin 1 has higher fluorescence yield but lower singlet o...

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Veröffentlicht in:	Photochemistry and photobiology 2010-01, Vol.86 (1), p.206-212
Hauptverfasser:	Serra, Arménio, Pineiro, Marta, Santos, Catarina Isabel, Rocha Gonsalves, António Manuel d'A., Abrantes, Margarida, Laranjo, Mafalda, Botelho, Maria Filomena
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Cancer Cancer therapies Cell Line, Tumor Chemical synthesis Colorectal Neoplasms - pathology Colorectal Neoplasms - therapy Drug resistance Gastroenterology Halogenation Humans Melanoma - pathology Melanoma - therapy Molecular weight NMR Nuclear magnetic resonance Photochemotherapy - methods Photodynamic therapy Porphyrins - pharmacology Porphyrins - therapeutic use Studies
Online-Zugang:	Volltext
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