Role of Ubiquitin C-Terminal Hydrolase-L1 in Antipolyspermy Defense of Mammalian Oocytes

The ubiquitin-proteasome system regulates many cellular processes through rapid proteasomal degradation of ubiquitin-tagged proteins. Ubiquitin C-terminal hydrolase-L1 (UCHL1) is one of the most abundant proteins in mammalian oocytes. It has weak hydrolytic activity as a monomer and acts as a ubiqui...

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Veröffentlicht in:	Biology of reproduction 2010-06, Vol.82 (6), p.1151-1161
Hauptverfasser:	Susor, Andrej, Liskova, Lucie, Toralova, Tereza, Pavlok, Antonin, Pivonkova, Katerina, Karabinova, Pavla, Lopatarova, Miloslava, Sutovsky, Peter, Kubelka, Michal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cattle Female Fertilization Fertilization in Vitro Fundamental and applied biological sciences. Psychology Oocytes - enzymology Polyubiquitin - analysis Ubiquitin C - analysis Ubiquitin Thiolesterase - antagonists & inhibitors Ubiquitin Thiolesterase - metabolism Vertebrates: reproduction Zygote - enzymology
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