Dramatic response of a patient with pregnancy induced idiopathic pulmonary arterial hypertension to sildenafil treatment

Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complicatio...

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Veröffentlicht in:The journal of obstetrics and gynaecology research 2010-04, Vol.36 (2), p.414-417
Hauptverfasser: Taçoy, Gülten, Ekim, Numan Nadir, Çengel, Atiye
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container_title The journal of obstetrics and gynaecology research
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creator Taçoy, Gülten
Ekim, Numan Nadir
Çengel, Atiye
description Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complications of pulmonary arterial hypertension (PAH). A patient diagnosed with IPAH after a successful full‐term pregnancy and cesarean section with epidural anesthesia is presented. The postoperative course was complicated by progressive dyspnea, and lower limb edema. The outcome of treatment with sildenafil during puerperium was favorable in this patient. The clinical course was complicated by an unexpected spontaneous pregnancy after primary infertility.
doi_str_mv 10.1111/j.1447-0756.2009.01136.x
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subjects Female
Humans
Hypertension, Pregnancy-Induced - drug therapy
Hypertension, Pulmonary - drug therapy
idiopathic pulmonary arterial hypertension
Piperazines - therapeutic use
Pregnancy
Purines - therapeutic use
sildenafil
Sildenafil Citrate
Sulfones - therapeutic use
treatment
Treatment Outcome
Vasodilator Agents - therapeutic use
title Dramatic response of a patient with pregnancy induced idiopathic pulmonary arterial hypertension to sildenafil treatment
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