The inhibition of thrombin and chymotrypsin by heparin-cofactor II

Heparin cofactor II (HC II) is known as a bifunctional inhibitor inactivating trypsin- and chymotrypsin type proteases. Its inhibitory activity increases in the presence of heparin, dermatan sulfate and chondroitin E. In the present study the inhibitory activity of HC II was investigated as function...

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Veröffentlicht in:	Thrombosis research 1992-10, Vol.68 (1), p.45-56
Hauptverfasser:	Struβ, D., Storck, J., Zimmermann, R.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	antithrombin Chloramines chymotrypsin Chymotrypsin - antagonists & inhibitors dermatan sulfate Dermatan Sulfate - pharmacology Heparin cofactor II Heparin Cofactor II - chemistry Heparin Cofactor II - pharmacology oxidation Periodic Acid Thrombin - antagonists & inhibitors Tosyl Compounds
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