Novel multifunctional pharmaceutical excipients derived from microcrystalline cellulose–starch microparticulate composites prepared by compatibilized reactive polymer blending

The choice of excipients remains a critical factor in pharmaceutical formulations. Microcrystalline cellulose–maize starch composites (MCC–Mst) have been prepared by mixing colloidal dispersions of microcrystalline cellulose (MCC) with 10% (w/w) of chemically gelatinized maize starch (Mst) at contro...

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Veröffentlicht in:	International journal of pharmaceutics 2010-03, Vol.388 (1), p.159-167
Hauptverfasser:	Builders, Philip F., Bonaventure, Agbo M., Tiwalade, Adelakun, Okpako, Larry C., Attama, Anthony A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - administration & dosage Acetaminophen - chemistry Aspirin - administration & dosage Aspirin - chemistry Biological and medical sciences Calorimetry, Differential Scanning Cellulose - chemistry Chemistry, Pharmaceutical - methods Direct compression Excipients - chemistry Freezing General pharmacology Hardness Maize starch Medical sciences Microcrystalline cellulose Microcrystalline cellulose–maize starch composites Microscopy, Electron, Scanning Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Starch - chemistry Tablets Temperature Time Factors Zea mays - chemistry
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