Conformational plasticity of recombinant bovine prion protein

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a special class of neurodegenerative diseases occurring both in humans and animals. TSE pathogenesis is determined by the transition of the native spatial conformation of the cellular protein prion (PrPc), which consist primari...

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Veröffentlicht in:	Doklady. Biochemistry and biophysics 2010-02, Vol.430 (1), p.17-19
Hauptverfasser:	Grigoriev, V. B., Kalnov, S. L., Pokidyshev, A. N., Klimenko, S. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biomedical research Biophysics Biophysics and Molecular Biology Cattle Cellular biology Life Sciences Microscopy, Electron Neurological disorders Prions Prions - chemistry Protein Conformation Protein Denaturation Recombinant Proteins - chemistry
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