Epilepsy surgery in infancy: A review of four cases
It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children's Healt...
Gespeichert in:
| Veröffentlicht in: | Pediatric neurosurgery 2003-07, Vol.39 (1), p.44-49 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 49 |
|---|---|
| container_issue | 1 |
| container_start_page | 44 |
| container_title | Pediatric neurosurgery |
| container_volume | 39 |
| creator | OLAVARRIA, Greg PETRONIO, Joseph A |
| description | It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children's Healthcare of Atlanta Egleston Hospital between 1994 and 2002. All infants, ranging in age from 5 to 9 months, presented with severe seizure disorders and failed trials of anticonvulsants. All had preoperative EEG monitoring and MRI studies; 2 had PET functional imaging. One infant underwent a temporal resection for a low-grade glioma. The rest had cortical resections for malformations and dysplasia. All had improvement, with 2 infants free of seizures off medication. We argue for early intervention in severe cases, as the potential for recovery can be dramatic. |
| doi_str_mv | 10.1159/000070880 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_73353580</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>677586931</sourcerecordid><originalsourceid>FETCH-LOGICAL-p264t-6e277e3d8deef219d22407a9582bd423ffc036c222102eb92e450baecc51c0ac3</originalsourceid><addsrcrecordid>eNpd0E1LxDAQBuAgiruuHvwDUgS9VSeTpk29Lcv6AQte9FzSdCJdum1Ntkr_vRErgiGQOTzkfRnGzjnccC7zWwgnA6XggM15giIGAfIwzMDTGDHnM3bi_RYg4Dw5ZjOOmUogU3Mm1n3dUO_HyA_ujdwY1W24VrdmvIuWkaOPmj6jzka2G1xktCd_yo6sbjydTe-Cvd6vX1aP8eb54Wm13MQ9psk-TgmzjESlKiKLPK8QQ6bOpcKyCi2tNSBSg4gckMocKZFQajJGcgPaiAW7_vm3d937QH5f7GpvqGl0S93gi0wIKaSCAC__wW0o24ZuRcjkkoNUAV1MaCh3VBW9q3fajcXvLgK4moD2RjfWhR3U_s8lKhffiV-HyGnd</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>224151058</pqid></control><display><type>article</type><title>Epilepsy surgery in infancy: A review of four cases</title><source>MEDLINE</source><source>Karger Journals</source><creator>OLAVARRIA, Greg ; PETRONIO, Joseph A</creator><creatorcontrib>OLAVARRIA, Greg ; PETRONIO, Joseph A</creatorcontrib><description>It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children's Healthcare of Atlanta Egleston Hospital between 1994 and 2002. All infants, ranging in age from 5 to 9 months, presented with severe seizure disorders and failed trials of anticonvulsants. All had preoperative EEG monitoring and MRI studies; 2 had PET functional imaging. One infant underwent a temporal resection for a low-grade glioma. The rest had cortical resections for malformations and dysplasia. All had improvement, with 2 infants free of seizures off medication. We argue for early intervention in severe cases, as the potential for recovery can be dramatic.</description><identifier>ISSN: 1016-2291</identifier><identifier>EISSN: 1423-0305</identifier><identifier>DOI: 10.1159/000070880</identifier><identifier>PMID: 12784078</identifier><identifier>CODEN: PDNEEV</identifier><language>eng</language><publisher>Basel: Karger</publisher><subject>Biological and medical sciences ; Electroencephalography ; Epilepsy ; Epilepsy - diagnosis ; Epilepsy - physiopathology ; Epilepsy - surgery ; Female ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Humans ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Neurosurgical Procedures ; Outcome Assessment (Health Care) ; Tomography, Emission-Computed ; Tomography, X-Ray Computed</subject><ispartof>Pediatric neurosurgery, 2003-07, Vol.39 (1), p.44-49</ispartof><rights>2003 INIST-CNRS</rights><rights>Copyright 2003 S. Karger AG, Basel</rights><rights>Copyright (c) 2003 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14893335$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12784078$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>OLAVARRIA, Greg</creatorcontrib><creatorcontrib>PETRONIO, Joseph A</creatorcontrib><title>Epilepsy surgery in infancy: A review of four cases</title><title>Pediatric neurosurgery</title><addtitle>Pediatr Neurosurg</addtitle><description>It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children's Healthcare of Atlanta Egleston Hospital between 1994 and 2002. All infants, ranging in age from 5 to 9 months, presented with severe seizure disorders and failed trials of anticonvulsants. All had preoperative EEG monitoring and MRI studies; 2 had PET functional imaging. One infant underwent a temporal resection for a low-grade glioma. The rest had cortical resections for malformations and dysplasia. All had improvement, with 2 infants free of seizures off medication. We argue for early intervention in severe cases, as the potential for recovery can be dramatic.</description><subject>Biological and medical sciences</subject><subject>Electroencephalography</subject><subject>Epilepsy</subject><subject>Epilepsy - diagnosis</subject><subject>Epilepsy - physiopathology</subject><subject>Epilepsy - surgery</subject><subject>Female</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Neurosurgical Procedures</subject><subject>Outcome Assessment (Health Care)</subject><subject>Tomography, Emission-Computed</subject><subject>Tomography, X-Ray Computed</subject><issn>1016-2291</issn><issn>1423-0305</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpd0E1LxDAQBuAgiruuHvwDUgS9VSeTpk29Lcv6AQte9FzSdCJdum1Ntkr_vRErgiGQOTzkfRnGzjnccC7zWwgnA6XggM15giIGAfIwzMDTGDHnM3bi_RYg4Dw5ZjOOmUogU3Mm1n3dUO_HyA_ujdwY1W24VrdmvIuWkaOPmj6jzka2G1xktCd_yo6sbjydTe-Cvd6vX1aP8eb54Wm13MQ9psk-TgmzjESlKiKLPK8QQ6bOpcKyCi2tNSBSg4gckMocKZFQajJGcgPaiAW7_vm3d937QH5f7GpvqGl0S93gi0wIKaSCAC__wW0o24ZuRcjkkoNUAV1MaCh3VBW9q3fajcXvLgK4moD2RjfWhR3U_s8lKhffiV-HyGnd</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>OLAVARRIA, Greg</creator><creator>PETRONIO, Joseph A</creator><general>Karger</general><general>S. Karger AG</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>L.-</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20030701</creationdate><title>Epilepsy surgery in infancy: A review of four cases</title><author>OLAVARRIA, Greg ; PETRONIO, Joseph A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p264t-6e277e3d8deef219d22407a9582bd423ffc036c222102eb92e450baecc51c0ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Biological and medical sciences</topic><topic>Electroencephalography</topic><topic>Epilepsy</topic><topic>Epilepsy - diagnosis</topic><topic>Epilepsy - physiopathology</topic><topic>Epilepsy - surgery</topic><topic>Female</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Neurosurgical Procedures</topic><topic>Outcome Assessment (Health Care)</topic><topic>Tomography, Emission-Computed</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>OLAVARRIA, Greg</creatorcontrib><creatorcontrib>PETRONIO, Joseph A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>OLAVARRIA, Greg</au><au>PETRONIO, Joseph A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epilepsy surgery in infancy: A review of four cases</atitle><jtitle>Pediatric neurosurgery</jtitle><addtitle>Pediatr Neurosurg</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>39</volume><issue>1</issue><spage>44</spage><epage>49</epage><pages>44-49</pages><issn>1016-2291</issn><eissn>1423-0305</eissn><coden>PDNEEV</coden><abstract>It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children's Healthcare of Atlanta Egleston Hospital between 1994 and 2002. All infants, ranging in age from 5 to 9 months, presented with severe seizure disorders and failed trials of anticonvulsants. All had preoperative EEG monitoring and MRI studies; 2 had PET functional imaging. One infant underwent a temporal resection for a low-grade glioma. The rest had cortical resections for malformations and dysplasia. All had improvement, with 2 infants free of seizures off medication. We argue for early intervention in severe cases, as the potential for recovery can be dramatic.</abstract><cop>Basel</cop><pub>Karger</pub><pmid>12784078</pmid><doi>10.1159/000070880</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1016-2291 |
| ispartof | Pediatric neurosurgery, 2003-07, Vol.39 (1), p.44-49 |
| issn | 1016-2291 1423-0305 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73353580 |
| source | MEDLINE; Karger Journals |
| subjects | Biological and medical sciences Electroencephalography Epilepsy Epilepsy - diagnosis Epilepsy - physiopathology Epilepsy - surgery Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Infant Infant, Newborn Magnetic Resonance Imaging Male Medical sciences Nervous system (semeiology, syndromes) Neurology Neurosurgical Procedures Outcome Assessment (Health Care) Tomography, Emission-Computed Tomography, X-Ray Computed |
| title | Epilepsy surgery in infancy: A review of four cases |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T08%3A02%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Epilepsy%20surgery%20in%20infancy:%20A%20review%20of%20four%20cases&rft.jtitle=Pediatric%20neurosurgery&rft.au=OLAVARRIA,%20Greg&rft.date=2003-07-01&rft.volume=39&rft.issue=1&rft.spage=44&rft.epage=49&rft.pages=44-49&rft.issn=1016-2291&rft.eissn=1423-0305&rft.coden=PDNEEV&rft_id=info:doi/10.1159/000070880&rft_dat=%3Cproquest_pubme%3E677586931%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=224151058&rft_id=info:pmid/12784078&rfr_iscdi=true |