Response to Smallpox Vaccine in Persons Immunized in the Distant Past

CONTEXT There is renewed interest in use of smallpox vaccine due to the potential for a bioterrorist attack. This would involve vaccinating health care workers who were previously vaccinated. OBJECTIVE To evaluate the use of diluted vaccinia virus in vaccination of previously vaccinated (non-naive)...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2003-06, Vol.289 (24), p.3295-3299
Hauptverfasser:	Frey, Sharon E, Newman, Frances K, Yan, Lihan, Belshe, Robert B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Viral - blood Biological and medical sciences Human viral diseases Humans Immunization Immunization, Secondary - adverse effects Immunologic Memory Infectious diseases Medical sciences Middle Aged Single-Blind Method Skin Diseases, Papulosquamous - etiology Skin Diseases, Papulosquamous - immunology Skin Diseases, Papulosquamous - virology Smallpox Smallpox Vaccine - administration & dosage Smallpox Vaccine - adverse effects Smallpox Vaccine - immunology Vaccination - adverse effects Vaccines Vaccinia virus - isolation & purification Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye Virus Shedding
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