Ammonium persulfate can initiate an asthmatic response in mice

BackgroundPersulfate salts are the main cause of occupational asthma (OA) in hairdressers. The aim of this study was to verify whether ammonium persulfate ((NH4)2S2O8, AP) is capable of triggering an asthma-like response in mice.MethodsBALB/c mice were dermally treated on days 1 and 8, with dimethyl...

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Veröffentlicht in:	Thorax 2010-03, Vol.65 (3), p.252-257
Hauptverfasser:	De Vooght, Vanessa, Cruz, María-Jesús, Haenen, Steven, Wijnhoven, Katlijn, Muñoz, Xavier, Hoet, Peter HM, Morell, Ferran, Nemery, Benoit, Vanoirbeek, Jeroen AJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonium persulfate Ammonium Sulfate - toxicity Animals Asthma Asthma - chemically induced Asthma - immunology Asthma - physiopathology Biological and medical sciences Bronchial Hyperreactivity - chemically induced Bronchoconstrictor Agents Cardiology. Vascular system Cell Proliferation - drug effects Cells, Cultured Chronic obstructive pulmonary disease, asthma Cytokines - metabolism Disease Models, Animal Dose-Response Relationship, Drug Hairdressers Immunoglobulin E - blood Immunology Lymph Nodes - immunology Lymphatic system Lymphocyte Activation - drug effects lymphocyte proliferation test (LPT) Lymphocytes Male Medical sciences Methacholine Chloride Mice Mice, Inbred BALB C murine model occupational asthma Pneumology Th lymphocytes
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