The role of microRNAs in normal and malignant hematopoiesis

MicroRNAs are small non‐coding RNAs that act at the post‐transcriptional level, regulating protein expression by repressing translation or destabilizing mRNA target. Because of their discovery, microRNAs have been associated with almost every normal cell function, including proliferation, differenti...

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Veröffentlicht in:	European journal of haematology 2010-01, Vol.84 (1), p.1-16
Hauptverfasser:	Vasilatou, Diamantina, Papageorgiou, Sotirios, Pappa, Vassiliki, Papageorgiou, Efstathios, Dervenoulas, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Transformation, Neoplastic - genetics Down-Regulation Erythroid Precursor Cells - cytology Gene Expression Regulation - genetics Gene Expression Regulation, Neoplastic - genetics Genes, Tumor Suppressor Hematologic Neoplasms - genetics Hematologic Neoplasms - pathology hematopoiesis Hematopoiesis - genetics Humans Invertebrates - genetics leukemia Lymphocytes - cytology lymphomas Mice microRNAs MicroRNAs - antagonists & inhibitors MicroRNAs - genetics MicroRNAs - physiology Myeloid Cells - cytology Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics non-protein-coding RNAs Oncogenes RNA, Neoplasm - antagonists & inhibitors RNA, Neoplasm - genetics
Online-Zugang:	Volltext
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