Aging-Related Nicotinamide Adenine Dinucleotide Oxidase Response to Dietary Supplementation: The French Paradox Revisited

Aging-related cell-surface NADH oxidase (arNOX)-specific activities increase with age between age 30 and ages 50–65. The protein is shed and circulates. Activity correlates with a number of aging-related disorders including low-density lipoprotein (LDL) oxidation as a precondition to atherosclerosis...

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Veröffentlicht in:	Rejuvenation research 2010-04, Vol.13 (2-3), p.159-161
Hauptverfasser:	Morré, D. James, Morré, Dorothy M., Shelton, Thomas B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging Aging - blood Aging - metabolism Atherosclerosis - blood Atherosclerosis - etiology Atherosclerosis - metabolism Biological Products - administration & dosage Biological Products - pharmacology Dietary Supplements Dosage and administration Female France Health aspects Humans Life Style Lipoproteins, LDL - analysis Lipoproteins, LDL - blood Male Middle Aged NAD (Coenzyme) NAD - metabolism NADH, NADPH Oxidoreductases - analysis NADH, NADPH Oxidoreductases - blood NADH, NADPH Oxidoreductases - metabolism Nutritional Physiological Phenomena - drug effects Oxidation-Reduction - drug effects Oxidative Damage Superoxides - metabolism
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