Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola
Four new ent-kaurane diterpenoids (16R)-ent-kauran-17,19-diol (1), (16R)-17-hydroxy-ent-kauran-19-oic acid (2), (16S)-17-hydroxy-ent-kauran-19-oic acid (3), and (16R)-17-dimethoxy-ent-kauran-19-oic acid (4) have been isolated from the fresh fruits of Annona cherimola together with eight known compou...
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Veröffentlicht in: | Chemical & pharmaceutical bulletin 2010/05/01, Vol.58(5), pp.765-768 |
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creator | Miyashita, Hiroyuki Nishida, Makiko Okawa, Masafumi Nohara, Toshihiro Yoshimitsu, Hitoshi |
description | Four new ent-kaurane diterpenoids (16R)-ent-kauran-17,19-diol (1), (16R)-17-hydroxy-ent-kauran-19-oic acid (2), (16S)-17-hydroxy-ent-kauran-19-oic acid (3), and (16R)-17-dimethoxy-ent-kauran-19-oic acid (4) have been isolated from the fresh fruits of Annona cherimola together with eight known compounds. Their structures are determined on the basis of spectroscopic data and optical rotation. |
doi_str_mv | 10.1248/cpb.58.765 |
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Their structures are determined on the basis of spectroscopic data and optical rotation.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.58.765</identifier><identifier>PMID: 20460813</identifier><language>eng</language><publisher>Japan: The Pharmaceutical Society of Japan</publisher><subject>Annona - chemistry ; Annona cherimola ; Annonaceae ; Diterpenes - chemistry ; Diterpenes, Kaurane - chemistry ; Diterpenes, Kaurane - isolation & purification ; diterpenoid ; ent-kaurane ; Fruit - chemistry ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Plant Extracts - chemistry</subject><ispartof>Chemical and Pharmaceutical Bulletin, 2010/05/01, Vol.58(5), pp.765-768</ispartof><rights>2010 The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-e82d4e3eca6f3bebfa53955769ea6e4c260b474246862310bcc03d62fd2c69413</citedby><cites>FETCH-LOGICAL-c472t-e82d4e3eca6f3bebfa53955769ea6e4c260b474246862310bcc03d62fd2c69413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,1884,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20460813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miyashita, Hiroyuki</creatorcontrib><creatorcontrib>Nishida, Makiko</creatorcontrib><creatorcontrib>Okawa, Masafumi</creatorcontrib><creatorcontrib>Nohara, Toshihiro</creatorcontrib><creatorcontrib>Yoshimitsu, Hitoshi</creatorcontrib><title>Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola</title><title>Chemical & pharmaceutical bulletin</title><addtitle>Chem. 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Their structures are determined on the basis of spectroscopic data and optical rotation.</description><subject>Annona - chemistry</subject><subject>Annona cherimola</subject><subject>Annonaceae</subject><subject>Diterpenes - chemistry</subject><subject>Diterpenes, Kaurane - chemistry</subject><subject>Diterpenes, Kaurane - isolation & purification</subject><subject>diterpenoid</subject><subject>ent-kaurane</subject><subject>Fruit - chemistry</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Molecular Structure</subject><subject>Plant Extracts - chemistry</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkMtKxDAUhoMoznjZ-AAScCEIHdPc2qxERkfFQTe6Dml66nRom5q0iG9vhvECbs5ZnI-P8_8InaRkllKeX9q-mIl8lkmxg6Yp41kiKGW7aEoIUQllkk3QQQhrQqggGdtHE0q4JHnKpuh24UaPn-ADQzckj2b0pgN8Uw_ge-hcXQZcedfiYQV44cd6CNhV-LrrXGewXYGvW9eYI7RXmSbA8fc-RK-L25f5fbJ8vnuYXy8TyzM6JJDTkgMDa2TFCigqI5gSIpMKjARuqSQFzzjlMpeUpaSwlrBS0qqkViqeskN0vvX23r2PEAbd1sFC08Sn3Rh0xpggSjEVybN_5DoG7eJzOo3ZOVVSbXwXW8p6F4KHSvcxkPGfOiV6062O3WqR69hthE-_lWPRQvmL_pQZgastsA6DeYNfwPihtg38uMR2ROXfZWW8ho59AU0Vic8</recordid><startdate>20100501</startdate><enddate>20100501</enddate><creator>Miyashita, Hiroyuki</creator><creator>Nishida, Makiko</creator><creator>Okawa, Masafumi</creator><creator>Nohara, Toshihiro</creator><creator>Yoshimitsu, Hitoshi</creator><general>The Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20100501</creationdate><title>Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola</title><author>Miyashita, Hiroyuki ; Nishida, Makiko ; Okawa, Masafumi ; Nohara, Toshihiro ; Yoshimitsu, Hitoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-e82d4e3eca6f3bebfa53955769ea6e4c260b474246862310bcc03d62fd2c69413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Annona - chemistry</topic><topic>Annona cherimola</topic><topic>Annonaceae</topic><topic>Diterpenes - chemistry</topic><topic>Diterpenes, Kaurane - chemistry</topic><topic>Diterpenes, Kaurane - isolation & purification</topic><topic>diterpenoid</topic><topic>ent-kaurane</topic><topic>Fruit - chemistry</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Molecular Structure</topic><topic>Plant Extracts - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miyashita, Hiroyuki</creatorcontrib><creatorcontrib>Nishida, Makiko</creatorcontrib><creatorcontrib>Okawa, Masafumi</creatorcontrib><creatorcontrib>Nohara, Toshihiro</creatorcontrib><creatorcontrib>Yoshimitsu, Hitoshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical & pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miyashita, Hiroyuki</au><au>Nishida, Makiko</au><au>Okawa, Masafumi</au><au>Nohara, Toshihiro</au><au>Yoshimitsu, Hitoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola</atitle><jtitle>Chemical & pharmaceutical bulletin</jtitle><addtitle>Chem. Pharm. Bull.</addtitle><date>2010-05-01</date><risdate>2010</risdate><volume>58</volume><issue>5</issue><spage>765</spage><epage>768</epage><pages>765-768</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><abstract>Four new ent-kaurane diterpenoids (16R)-ent-kauran-17,19-diol (1), (16R)-17-hydroxy-ent-kauran-19-oic acid (2), (16S)-17-hydroxy-ent-kauran-19-oic acid (3), and (16R)-17-dimethoxy-ent-kauran-19-oic acid (4) have been isolated from the fresh fruits of Annona cherimola together with eight known compounds. Their structures are determined on the basis of spectroscopic data and optical rotation.</abstract><cop>Japan</cop><pub>The Pharmaceutical Society of Japan</pub><pmid>20460813</pmid><doi>10.1248/cpb.58.765</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Annona - chemistry Annona cherimola Annonaceae Diterpenes - chemistry Diterpenes, Kaurane - chemistry Diterpenes, Kaurane - isolation & purification diterpenoid ent-kaurane Fruit - chemistry Magnetic Resonance Spectroscopy Molecular Structure Plant Extracts - chemistry |
title | Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola |
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