Extremely rare incidence of the UBQLN1 polymorphism (UBQ-8i) in Taiwan Chinese with Alzheimer's disease

Recently, a single nucleotide polymorphism (SNP, A → G) in intron 8 of UBQLN 1 at the rs12344615 site (UBQ-8i) on chromosome 9q22 was associated with a higher risk of late-onset Alzheimer's disease (AD). Here, we aimed to investigate whether an association exists between the UBQ-8i polymorphism...

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Veröffentlicht in:	Neuroscience letters 2010-05, Vol.475 (2), p.108-109
Hauptverfasser:	Chuo, Liang-Jen, Wu, Shwu-Tzy, Chang, Hong-I., Kuo, Yu-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - genetics Alzheimer's disease Apolipoprotein E4 - genetics Asian Continental Ancestry Group Biological and medical sciences Carrier Proteins - genetics Cell Cycle Proteins - genetics Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Fundamental and applied biological sciences. Psychology Genetic Association Studies Genetic Predisposition to Disease Humans Male Medical sciences Neurology Polymorphism Polymorphism, Single Nucleotide Taiwan Ubiquilin 1 Vertebrates: nervous system and sense organs
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