Treatment of choroidal melanoma using photodynamic therapy
To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma. Interventional case series. Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary therm...
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| Veröffentlicht in: | American journal of ophthalmology 2003-06, Vol.135 (6), p.898-899 |
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| container_title | American journal of ophthalmology |
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| creator | Barbazetto, Irene A. Lee, Thomas C. Rollins, Indira S. Chang, Stanley Abramson, David H. |
| description | To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma.
Interventional case series.
Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy.
One tumor decreased in size and remained stable for 18 months. One tumor had no growth for 11 months. Two melanomas continued to grow, necessitating enucleation.
Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma. |
| doi_str_mv | 10.1016/S0002-9394(02)02222-5 |
| format | Article |
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Interventional case series.
Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy.
One tumor decreased in size and remained stable for 18 months. One tumor had no growth for 11 months. Two melanomas continued to grow, necessitating enucleation.
Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma.</description><identifier>ISSN: 0002-9394</identifier><identifier>EISSN: 1879-1891</identifier><identifier>DOI: 10.1016/S0002-9394(02)02222-5</identifier><identifier>PMID: 12788137</identifier><identifier>CODEN: AJOPAA</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Biological and medical sciences ; Choroid Neoplasms - diagnostic imaging ; Choroid Neoplasms - drug therapy ; Humans ; Macular degeneration ; Medical sciences ; Melanoma - diagnostic imaging ; Melanoma - drug therapy ; Middle Aged ; Ophthalmology ; Photochemotherapy ; Photodynamic therapy ; Photosensitizing Agents - therapeutic use ; Porphyrins - therapeutic use ; Radiation therapy ; Skin cancer ; Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus ; Ultrasonography ; Verteporfin</subject><ispartof>American journal of ophthalmology, 2003-06, Vol.135 (6), p.898-899</ispartof><rights>2003 Elsevier Inc.</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-a37504c225874b2f75430c32a7dd87fb9a7218760a4acf099af0625267fede0c3</citedby><cites>FETCH-LOGICAL-c471t-a37504c225874b2f75430c32a7dd87fb9a7218760a4acf099af0625267fede0c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0002-9394(02)02222-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14869090$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12788137$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barbazetto, Irene A.</creatorcontrib><creatorcontrib>Lee, Thomas C.</creatorcontrib><creatorcontrib>Rollins, Indira S.</creatorcontrib><creatorcontrib>Chang, Stanley</creatorcontrib><creatorcontrib>Abramson, David H.</creatorcontrib><title>Treatment of choroidal melanoma using photodynamic therapy</title><title>American journal of ophthalmology</title><addtitle>Am J Ophthalmol</addtitle><description>To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma.
Interventional case series.
Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy.
One tumor decreased in size and remained stable for 18 months. One tumor had no growth for 11 months. Two melanomas continued to grow, necessitating enucleation.
Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Choroid Neoplasms - diagnostic imaging</subject><subject>Choroid Neoplasms - drug therapy</subject><subject>Humans</subject><subject>Macular degeneration</subject><subject>Medical sciences</subject><subject>Melanoma - diagnostic imaging</subject><subject>Melanoma - drug therapy</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>Photochemotherapy</subject><subject>Photodynamic therapy</subject><subject>Photosensitizing Agents - therapeutic use</subject><subject>Porphyrins - therapeutic use</subject><subject>Radiation therapy</subject><subject>Skin cancer</subject><subject>Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus</subject><subject>Ultrasonography</subject><subject>Verteporfin</subject><issn>0002-9394</issn><issn>1879-1891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0F1LHDEUBuBQLHW1_QmVAVHsxbRJJjNJvClFtAqCF91eh7OZEzcyM1mTmcL-e7MfVPDG3BwCzzm8vIR8ZfQ7o6z58YdSyktdaXFB-TfK8yvrD2TGlNQlU5odkNl_ckiOUnrK30YK-YkcMi6VYpWckct5RBh7HMYiuMIuQwy-ha7osYMh9FBMyQ-PxWoZxtCuB-i9LcYlRlitP5OPDrqEX_bzmPy9uZ5f3Zb3D7_vrn7dl1ZINpZQyZoKy3mtpFhwJ2tRUVtxkG2rpFtokDyHbigIsI5qDY42vOaNdNhilsfkfHd3FcPzhGk0vU8WuxwQw5SMrCqhpNIZnr6BT2GKQ85mGOMqK1ZtVL1TNoaUIjqzir6HuDaMmk21Zlut2fRm8txWa-q8d7K_Pi16bF-39l1mcLYHkCx0LsJgfXp1QjWaaprdz53DXNo_j9Ek63Gw2PqIdjRt8O9EeQGQYZPE</recordid><startdate>20030601</startdate><enddate>20030601</enddate><creator>Barbazetto, Irene A.</creator><creator>Lee, Thomas C.</creator><creator>Rollins, Indira S.</creator><creator>Chang, Stanley</creator><creator>Abramson, David H.</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20030601</creationdate><title>Treatment of choroidal melanoma using photodynamic therapy</title><author>Barbazetto, Irene A. ; Lee, Thomas C. ; Rollins, Indira S. ; Chang, Stanley ; Abramson, David H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-a37504c225874b2f75430c32a7dd87fb9a7218760a4acf099af0625267fede0c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Choroid Neoplasms - diagnostic imaging</topic><topic>Choroid Neoplasms - drug therapy</topic><topic>Humans</topic><topic>Macular degeneration</topic><topic>Medical sciences</topic><topic>Melanoma - diagnostic imaging</topic><topic>Melanoma - drug therapy</topic><topic>Middle Aged</topic><topic>Ophthalmology</topic><topic>Photochemotherapy</topic><topic>Photodynamic therapy</topic><topic>Photosensitizing Agents - therapeutic use</topic><topic>Porphyrins - therapeutic use</topic><topic>Radiation therapy</topic><topic>Skin cancer</topic><topic>Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus</topic><topic>Ultrasonography</topic><topic>Verteporfin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barbazetto, Irene A.</creatorcontrib><creatorcontrib>Lee, Thomas C.</creatorcontrib><creatorcontrib>Rollins, Indira S.</creatorcontrib><creatorcontrib>Chang, Stanley</creatorcontrib><creatorcontrib>Abramson, David H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barbazetto, Irene A.</au><au>Lee, Thomas C.</au><au>Rollins, Indira S.</au><au>Chang, Stanley</au><au>Abramson, David H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of choroidal melanoma using photodynamic therapy</atitle><jtitle>American journal of ophthalmology</jtitle><addtitle>Am J Ophthalmol</addtitle><date>2003-06-01</date><risdate>2003</risdate><volume>135</volume><issue>6</issue><spage>898</spage><epage>899</epage><pages>898-899</pages><issn>0002-9394</issn><eissn>1879-1891</eissn><coden>AJOPAA</coden><abstract>To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma.
Interventional case series.
Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy.
One tumor decreased in size and remained stable for 18 months. One tumor had no growth for 11 months. Two melanomas continued to grow, necessitating enucleation.
Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>12788137</pmid><doi>10.1016/S0002-9394(02)02222-5</doi><tpages>2</tpages></addata></record> |
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| ispartof | American journal of ophthalmology, 2003-06, Vol.135 (6), p.898-899 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Aged Aged, 80 and over Biological and medical sciences Choroid Neoplasms - diagnostic imaging Choroid Neoplasms - drug therapy Humans Macular degeneration Medical sciences Melanoma - diagnostic imaging Melanoma - drug therapy Middle Aged Ophthalmology Photochemotherapy Photodynamic therapy Photosensitizing Agents - therapeutic use Porphyrins - therapeutic use Radiation therapy Skin cancer Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus Ultrasonography Verteporfin |
| title | Treatment of choroidal melanoma using photodynamic therapy |
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