Removal of PSA from NCAM affects the survival of magnocellular vasopressin- and oxytocin-producing neurons in organotypic cultures of the paraventricular nucleus

The expression of the polysialic acid neural cell adhesion molecule (PSA‐NCAM) in the hypothalamo‐neurohypophyseal system has been correlated with morphofunctional plasticity. In this study, we investigated the role of PSA‐NCAM in the survival of oxytocin (OT)‐ and vasopressin (VP)‐producing magnoce...

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Veröffentlicht in:	The European journal of neuroscience 2003-05, Vol.17 (10), p.2119-2126
Hauptverfasser:	Vutskits, L., Gascon, E., Kiss, J. Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion molecules Animals Cell Survival - physiology Ciliary Neurotrophic Factor - pharmacology Glycoside Hydrolases - pharmacology growth factors Growth Inhibitors - pharmacology hypothalamus Interleukin-6 Leukemia Inhibitory Factor Lymphokines - pharmacology Male Membrane Proteins - metabolism Neural Cell Adhesion Molecule L1 - metabolism Neural Cell Adhesion Molecules - metabolism Neuronal Plasticity - physiology Neurons - cytology Neurons - drug effects Neurons - metabolism Organ Culture Techniques Oxytocin - biosynthesis Paraventricular Hypothalamic Nucleus - cytology rat Rats Rats, Sprague-Dawley Sialic Acids - metabolism Vasopressins - biosynthesis
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