three-dimensional structure of an intact monoclonal antibody for canine lymphoma
CRYSTAL structures of Fab antibody fragments determined by X-ray diffraction characteristically feature four-domain, beta-barrel arrangements. A human antibody Fc fragment has also been found to have four beta-barrel domains. The structures of a few intact antibodies have been solved: in two myeloma...
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Veröffentlicht in: | Nature (London) 1992-11, Vol.360 (6402), p.369-372 |
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