Body Weight-Related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects
To examine the serial time course of perioperative plasma ionized magnesium (iMg 2+ ) concentrations and to analyze the plasma iMg 2+ concentrations in children with different body mass who were undergoing open-heart surgery. Randomized, single-blinded study. University-affiliated hospital of an aca...
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| Veröffentlicht in: | Journal of clinical anesthesia 2003-05, Vol.15 (3), p.189-193 |
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| container_title | Journal of clinical anesthesia |
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| creator | Lu, Cheng-Yuan Tan, Ping-Heng Lin, Sheng-Han Tsai, Shen-Kou Lin, Su-Man Mao, Chih-Cheh Yang, Lin-Cheng |
| description | To examine the serial time course of perioperative plasma ionized magnesium (iMg
2+
) concentrations and to analyze the plasma iMg
2+
concentrations in children with different body mass who were undergoing open-heart surgery.
Randomized, single-blinded study.
University-affiliated hospital of an academic medical institution.
38 children undergoing open-heart surgery.
Patients were divided into three groups according to their body mass: Group 1 (n = 12) 20 kg.
The relationship of iMg
2+
among the three groups of different body mass were analyzed at five different time intervals during the operation: induction of anesthesia, 5 minutes and 30 minutes after the onset of cardiopulmonary bypass (CPB), the beginning of rewarming, and the end of surgery.
iMg
2+ levels at 5 minutes after onset of CPB in patients weighing less than 20 kg (Groups 1 and 2) differed with those weighing more than 20 kg (Group 3) (p = 0.007 and 0.013). However, there was no difference in the iMg
2+ levels between Groups 1 and 2 (p = 0.993). In addition, iMg
2+ levels at 5 minutes after onset of bypass correlated well (r
2 = 0.66) in children with body mass less than 20 kg.
Low levels of ionized magnesium is an important finding in patients at the onset of CPB, which correlates well with the body mass of patients weighing less than 20 kg, and could be predicted by the regression curve. Based on these findings, hypomagnesemia can be prevented during CPB. |
| doi_str_mv | 10.1016/S0952-8180(03)00031-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73342273</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S095281800300031X</els_id><sourcerecordid>73342273</sourcerecordid><originalsourceid>FETCH-LOGICAL-c419t-38fb6ca206aa75c89d8e94e96f97cf4b1bd0b3fbf284b1cfcaf7563042e531683</originalsourceid><addsrcrecordid>eNqFkcuKFTEQhoMozvHoIygBUXTRmnT6kl6JDt5gQPCCswvVSaUnQ3fSJt3C8Tl8YHMuOODGTYokXxXF_xHykLMXnPHm5RfW1WUhuWTPmHjOGBO8uLxFNly2oqjqsrtNNn-RM3IvpesM5Q9-l5zxsm1ZU1cb8vtNMDv6Hd1wtRSfcYQFDXXBu1-5Xu3mMMHgMeHkgDpPZzQOlug0nWFx6JdEV28wDsH5gWqIxoV5HafgIe5ov5shJWpDpGmNg9Mw0ogzuEiDpTr4Ab1b8uOhETQ1aFEv6T65Y2FM-OBUt-Tbu7dfzz8UF5_efzx_fVHoindLIaTtGw0lawDaWsvOSOwq7BrbtdpWPe8N64XtbSnzRVsNtq0bwaoSa8EbKbbk6XHuHMOPFdOiJpc0jiN4DGtSrRBVWeZzSx7_A16HNfq8m-JMVF3Lallnqj5SOoaUIlo1RzflIDKk9tLUQZraG1FMqIM0dZn7Hp2mr_2E5qbrZCkDT04ApJyhjeC1SzdcJVvJ-H7NV0cOc2g_HUaVdJaks7SYc1UmuP-s8gf4_rdu</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1034970585</pqid></control><display><type>article</type><title>Body Weight-Related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>ProQuest Central UK/Ireland</source><creator>Lu, Cheng-Yuan ; Tan, Ping-Heng ; Lin, Sheng-Han ; Tsai, Shen-Kou ; Lin, Su-Man ; Mao, Chih-Cheh ; Yang, Lin-Cheng</creator><creatorcontrib>Lu, Cheng-Yuan ; Tan, Ping-Heng ; Lin, Sheng-Han ; Tsai, Shen-Kou ; Lin, Su-Man ; Mao, Chih-Cheh ; Yang, Lin-Cheng</creatorcontrib><description>To examine the serial time course of perioperative plasma ionized magnesium (iMg
2+
) concentrations and to analyze the plasma iMg
2+
concentrations in children with different body mass who were undergoing open-heart surgery.
Randomized, single-blinded study.
University-affiliated hospital of an academic medical institution.
38 children undergoing open-heart surgery.
Patients were divided into three groups according to their body mass: Group 1 (n = 12) <10 kg, Group 2 (n = 13) 10 kg to 20 kg, and Group 3 (n = 13) >20 kg.
The relationship of iMg
2+
among the three groups of different body mass were analyzed at five different time intervals during the operation: induction of anesthesia, 5 minutes and 30 minutes after the onset of cardiopulmonary bypass (CPB), the beginning of rewarming, and the end of surgery.
iMg
2+ levels at 5 minutes after onset of CPB in patients weighing less than 20 kg (Groups 1 and 2) differed with those weighing more than 20 kg (Group 3) (p = 0.007 and 0.013). However, there was no difference in the iMg
2+ levels between Groups 1 and 2 (p = 0.993). In addition, iMg
2+ levels at 5 minutes after onset of bypass correlated well (r
2 = 0.66) in children with body mass less than 20 kg.
Low levels of ionized magnesium is an important finding in patients at the onset of CPB, which correlates well with the body mass of patients weighing less than 20 kg, and could be predicted by the regression curve. Based on these findings, hypomagnesemia can be prevented during CPB.</description><identifier>ISSN: 0952-8180</identifier><identifier>EISSN: 1873-4529</identifier><identifier>DOI: 10.1016/S0952-8180(03)00031-X</identifier><identifier>PMID: 12770654</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adults ; Anesthesia ; Anesthesia depending on type of surgery ; Anesthesia, general ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anticoagulants ; Biological and medical sciences ; Body Weight ; Cardiac arrhythmia ; Cardiopulmonary Bypass ; Child, Preschool ; congenital heart disease ; Female ; Heart Defects, Congenital - surgery ; Heart surgery ; Humans ; magnesium ; Magnesium - blood ; Magnesium - therapeutic use ; Magnesium Deficiency - blood ; Magnesium Deficiency - therapy ; Male ; Medical sciences ; Patients ; pediatric surgery ; Pediatrics ; Single-Blind Method ; Thoracic and cardiovascular surgery. Cardiopulmonary bypass ; Time Factors</subject><ispartof>Journal of clinical anesthesia, 2003-05, Vol.15 (3), p.189-193</ispartof><rights>2003 Elsevier Science Inc.</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-38fb6ca206aa75c89d8e94e96f97cf4b1bd0b3fbf284b1cfcaf7563042e531683</citedby><cites>FETCH-LOGICAL-c419t-38fb6ca206aa75c89d8e94e96f97cf4b1bd0b3fbf284b1cfcaf7563042e531683</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1034970585?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14878013$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12770654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Cheng-Yuan</creatorcontrib><creatorcontrib>Tan, Ping-Heng</creatorcontrib><creatorcontrib>Lin, Sheng-Han</creatorcontrib><creatorcontrib>Tsai, Shen-Kou</creatorcontrib><creatorcontrib>Lin, Su-Man</creatorcontrib><creatorcontrib>Mao, Chih-Cheh</creatorcontrib><creatorcontrib>Yang, Lin-Cheng</creatorcontrib><title>Body Weight-Related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects</title><title>Journal of clinical anesthesia</title><addtitle>J Clin Anesth</addtitle><description>To examine the serial time course of perioperative plasma ionized magnesium (iMg
2+
) concentrations and to analyze the plasma iMg
2+
concentrations in children with different body mass who were undergoing open-heart surgery.
Randomized, single-blinded study.
University-affiliated hospital of an academic medical institution.
38 children undergoing open-heart surgery.
Patients were divided into three groups according to their body mass: Group 1 (n = 12) <10 kg, Group 2 (n = 13) 10 kg to 20 kg, and Group 3 (n = 13) >20 kg.
The relationship of iMg
2+
among the three groups of different body mass were analyzed at five different time intervals during the operation: induction of anesthesia, 5 minutes and 30 minutes after the onset of cardiopulmonary bypass (CPB), the beginning of rewarming, and the end of surgery.
iMg
2+ levels at 5 minutes after onset of CPB in patients weighing less than 20 kg (Groups 1 and 2) differed with those weighing more than 20 kg (Group 3) (p = 0.007 and 0.013). However, there was no difference in the iMg
2+ levels between Groups 1 and 2 (p = 0.993). In addition, iMg
2+ levels at 5 minutes after onset of bypass correlated well (r
2 = 0.66) in children with body mass less than 20 kg.
Low levels of ionized magnesium is an important finding in patients at the onset of CPB, which correlates well with the body mass of patients weighing less than 20 kg, and could be predicted by the regression curve. Based on these findings, hypomagnesemia can be prevented during CPB.</description><subject>Adults</subject><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia, general</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anticoagulants</subject><subject>Biological and medical sciences</subject><subject>Body Weight</subject><subject>Cardiac arrhythmia</subject><subject>Cardiopulmonary Bypass</subject><subject>Child, Preschool</subject><subject>congenital heart disease</subject><subject>Female</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>magnesium</subject><subject>Magnesium - blood</subject><subject>Magnesium - therapeutic use</subject><subject>Magnesium Deficiency - blood</subject><subject>Magnesium Deficiency - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Patients</subject><subject>pediatric surgery</subject><subject>Pediatrics</subject><subject>Single-Blind Method</subject><subject>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</subject><subject>Time Factors</subject><issn>0952-8180</issn><issn>1873-4529</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkcuKFTEQhoMozvHoIygBUXTRmnT6kl6JDt5gQPCCswvVSaUnQ3fSJt3C8Tl8YHMuOODGTYokXxXF_xHykLMXnPHm5RfW1WUhuWTPmHjOGBO8uLxFNly2oqjqsrtNNn-RM3IvpesM5Q9-l5zxsm1ZU1cb8vtNMDv6Hd1wtRSfcYQFDXXBu1-5Xu3mMMHgMeHkgDpPZzQOlug0nWFx6JdEV28wDsH5gWqIxoV5HafgIe5ov5shJWpDpGmNg9Mw0ogzuEiDpTr4Ab1b8uOhETQ1aFEv6T65Y2FM-OBUt-Tbu7dfzz8UF5_efzx_fVHoindLIaTtGw0lawDaWsvOSOwq7BrbtdpWPe8N64XtbSnzRVsNtq0bwaoSa8EbKbbk6XHuHMOPFdOiJpc0jiN4DGtSrRBVWeZzSx7_A16HNfq8m-JMVF3Lallnqj5SOoaUIlo1RzflIDKk9tLUQZraG1FMqIM0dZn7Hp2mr_2E5qbrZCkDT04ApJyhjeC1SzdcJVvJ-H7NV0cOc2g_HUaVdJaks7SYc1UmuP-s8gf4_rdu</recordid><startdate>20030501</startdate><enddate>20030501</enddate><creator>Lu, Cheng-Yuan</creator><creator>Tan, Ping-Heng</creator><creator>Lin, Sheng-Han</creator><creator>Tsai, Shen-Kou</creator><creator>Lin, Su-Man</creator><creator>Mao, Chih-Cheh</creator><creator>Yang, Lin-Cheng</creator><general>Elsevier Inc</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20030501</creationdate><title>Body Weight-Related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects</title><author>Lu, Cheng-Yuan ; Tan, Ping-Heng ; Lin, Sheng-Han ; Tsai, Shen-Kou ; Lin, Su-Man ; Mao, Chih-Cheh ; Yang, Lin-Cheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-38fb6ca206aa75c89d8e94e96f97cf4b1bd0b3fbf284b1cfcaf7563042e531683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adults</topic><topic>Anesthesia</topic><topic>Anesthesia depending on type of surgery</topic><topic>Anesthesia, general</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anticoagulants</topic><topic>Biological and medical sciences</topic><topic>Body Weight</topic><topic>Cardiac arrhythmia</topic><topic>Cardiopulmonary Bypass</topic><topic>Child, Preschool</topic><topic>congenital heart disease</topic><topic>Female</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>magnesium</topic><topic>Magnesium - blood</topic><topic>Magnesium - therapeutic use</topic><topic>Magnesium Deficiency - blood</topic><topic>Magnesium Deficiency - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Patients</topic><topic>pediatric surgery</topic><topic>Pediatrics</topic><topic>Single-Blind Method</topic><topic>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lu, Cheng-Yuan</creatorcontrib><creatorcontrib>Tan, Ping-Heng</creatorcontrib><creatorcontrib>Lin, Sheng-Han</creatorcontrib><creatorcontrib>Tsai, Shen-Kou</creatorcontrib><creatorcontrib>Lin, Su-Man</creatorcontrib><creatorcontrib>Mao, Chih-Cheh</creatorcontrib><creatorcontrib>Yang, Lin-Cheng</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lu, Cheng-Yuan</au><au>Tan, Ping-Heng</au><au>Lin, Sheng-Han</au><au>Tsai, Shen-Kou</au><au>Lin, Su-Man</au><au>Mao, Chih-Cheh</au><au>Yang, Lin-Cheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Body Weight-Related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects</atitle><jtitle>Journal of clinical anesthesia</jtitle><addtitle>J Clin Anesth</addtitle><date>2003-05-01</date><risdate>2003</risdate><volume>15</volume><issue>3</issue><spage>189</spage><epage>193</epage><pages>189-193</pages><issn>0952-8180</issn><eissn>1873-4529</eissn><abstract>To examine the serial time course of perioperative plasma ionized magnesium (iMg
2+
) concentrations and to analyze the plasma iMg
2+
concentrations in children with different body mass who were undergoing open-heart surgery.
Randomized, single-blinded study.
University-affiliated hospital of an academic medical institution.
38 children undergoing open-heart surgery.
Patients were divided into three groups according to their body mass: Group 1 (n = 12) <10 kg, Group 2 (n = 13) 10 kg to 20 kg, and Group 3 (n = 13) >20 kg.
The relationship of iMg
2+
among the three groups of different body mass were analyzed at five different time intervals during the operation: induction of anesthesia, 5 minutes and 30 minutes after the onset of cardiopulmonary bypass (CPB), the beginning of rewarming, and the end of surgery.
iMg
2+ levels at 5 minutes after onset of CPB in patients weighing less than 20 kg (Groups 1 and 2) differed with those weighing more than 20 kg (Group 3) (p = 0.007 and 0.013). However, there was no difference in the iMg
2+ levels between Groups 1 and 2 (p = 0.993). In addition, iMg
2+ levels at 5 minutes after onset of bypass correlated well (r
2 = 0.66) in children with body mass less than 20 kg.
Low levels of ionized magnesium is an important finding in patients at the onset of CPB, which correlates well with the body mass of patients weighing less than 20 kg, and could be predicted by the regression curve. Based on these findings, hypomagnesemia can be prevented during CPB.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>12770654</pmid><doi>10.1016/S0952-8180(03)00031-X</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0952-8180 |
| ispartof | Journal of clinical anesthesia, 2003-05, Vol.15 (3), p.189-193 |
| issn | 0952-8180 1873-4529 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | Adults Anesthesia Anesthesia depending on type of surgery Anesthesia, general Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anticoagulants Biological and medical sciences Body Weight Cardiac arrhythmia Cardiopulmonary Bypass Child, Preschool congenital heart disease Female Heart Defects, Congenital - surgery Heart surgery Humans magnesium Magnesium - blood Magnesium - therapeutic use Magnesium Deficiency - blood Magnesium Deficiency - therapy Male Medical sciences Patients pediatric surgery Pediatrics Single-Blind Method Thoracic and cardiovascular surgery. Cardiopulmonary bypass Time Factors |
| title | Body Weight-Related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects |
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