Dietary cytidine (5′)-diphosphocholine supplementation protects against development of memory deficits in aging rats

The present study was designed to assess the effect of supplementation with dietary cytidine (5′)-diphosphocholine (CDP-choline), a source of cytidine and choline, on memory in young and older rats. Although the hippocampal-dependent memory deficits in aged rats are well documented, cognitive functi...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2003-06, Vol.27 (4), p.711-717
Hauptverfasser:	Teather, Lisa A., Wurtman, Richard J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Administration, Oral Aging Aging - psychology Animals Biological and medical sciences CDP-choline Cytidine Diphosphate Choline - administration & dosage Cytidine Diphosphate Choline - pharmacology Diet Disease Models, Animal Female General pharmacology Hippocampus Hippocampus - pathology Medical sciences Memory Memory Disorders - etiology Memory Disorders - prevention & control Nootropic Agents - administration & dosage Nootropic Agents - pharmacology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phospholipids Rats Rats, Sprague-Dawley
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