Impaired phagocytosis by alveolar macrophages from diabetic rats is related to the deficient coupling of LTs to the FcγR signaling cascade

Diabetic individuals are more susceptible to infections and this seems to be related to impaired phagocyte function. Alveolar macrophages (AMs) are the first barrier to prevent respiratory infections. Leukotrienes (LTs) increase AM phagocytic activity via FcγR. In this study, we compared AMs from di...

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Veröffentlicht in:Molecular immunology 2010-07, Vol.47 (11), p.1974-1980
Hauptverfasser: Ferracini, Matheus, Martins, Joilson O., Campos, Marina R.M., Anger, Denise B.C., Jancar, Sonia
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Sprache:eng
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