Cardioplegia and cardiac surgery: pharmacological arrest and cardioprotection during global ischemia and reperfusion

Since the start of cardiac surgery in the 1950s, multiple techniques have been used to protect the heart during the surgical requirement for elective global ischemia (and the still, relaxed, bloodless field that this provides the surgeon for repair of the lesion). Most of these techniques have been...

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Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 2010-07, Vol.127 (1), p.41-52
Hauptverfasser:	Chambers, David J, Fallouh, Hazem B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Channels - drug effects Cardioplegic Solutions - therapeutic use Cardiopulmonary Bypass Cardiotonic Agents - pharmacology Cardiotonic Agents - therapeutic use Heart Arrest, Induced - methods Humans Myocardial Ischemia - chemically induced Myocardial Reperfusion Sodium Channels - drug effects
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