Involvement of histamine 1 receptor in seizure susceptibility and neuroprotection in immature mice

Summary The central histaminergic neuronal system is a powerful modulator of brain activity, and its functional disturbance is related to e.g. epilepsy. We have recently shown in the slice culture system that histaminergic neurons attenuate kainic acid (KA)-induced epileptiform activity and neuronal...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Epilepsy research 2010-06, Vol.90 (1), p.8-15
Hauptverfasser:	Kukko-Lukjanov, Tiina-Kaisa, Lintunen, Minnamaija, Jalava, Niina, Laurén, Hanna B, Lopez-Picon, Francisco R, Michelsen, Kimmo A, Panula, Pertti, Holopainen, Irma E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Behavioral seizures Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Brain - metabolism Brain - pathology Cell Count - methods Chi-Square Distribution Developing mouse Disease Models, Animal Disease Susceptibility - physiopathology Dose-Response Relationship, Drug Epilepsy Fluoresceins Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Histamine 1 (H1) receptor Histamine H1 Antagonists - therapeutic use Kainic Acid Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Nervous system (semeiology, syndromes) Neurodegeneration Neurology Neuroprotection Organic Chemicals Pharmacology. Drug treatments Receptors, Histamine H1 - deficiency Receptors, Histamine H1 - metabolism Seizures - chemically induced Seizures - drug therapy Seizures - genetics Seizures - pathology Triprolidine - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!