Inflammatory pseudotumor of the parapharyngeal space: A case report
Abstract Inflammatory pseudotumor is an idiopathic granuloma characterized by infiltrative proliferation of inflammatory cells and myofibroblastic cells, as well as locally aggressive features, clinically and radiologically mimicking a neoplastic process. The occurrence of inflammatory pseudotumor i...
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| Veröffentlicht in: | Auris, nasus, larynx nasus, larynx, 2010-06, Vol.37 (3), p.397-400 |
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| creator | Maruya, Shin-ichiro Miura, Kouki Tada, Yu-ichiro Masubuchi, Tatsuo Nakamura, Narihiro Fushimi, Chihiro Sakashita, Tomohiro Monma, Tsutomu Kamata, Shin-etsu |
| description | Abstract Inflammatory pseudotumor is an idiopathic granuloma characterized by infiltrative proliferation of inflammatory cells and myofibroblastic cells, as well as locally aggressive features, clinically and radiologically mimicking a neoplastic process. The occurrence of inflammatory pseudotumor in the head and neck area is uncommon, especially in the parapharyngeal space. The case of a 54-year-old female with inflammatory pseudotumor of the parapharyngeal space is presented. The patient initially complained of hoarseness, dysarthria, aspiration, and hearing impairment. MRI disclosed an expansive soft mass in the parapharyngeal space encompassing the carotid arteries. Histopathologically, the lesions were composed of numerous plasma cells, lymphocytes, histiocytes, and spindle myofibroblastic cells, showing perineural infiltration of inflammatory cells. The patients’ symptoms, including conductive hearing loss, improved dramatically with reduction in lesion size after corticosteroid treatment. |
| doi_str_mv | 10.1016/j.anl.2009.08.002 |
| format | Article |
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The occurrence of inflammatory pseudotumor in the head and neck area is uncommon, especially in the parapharyngeal space. The case of a 54-year-old female with inflammatory pseudotumor of the parapharyngeal space is presented. The patient initially complained of hoarseness, dysarthria, aspiration, and hearing impairment. MRI disclosed an expansive soft mass in the parapharyngeal space encompassing the carotid arteries. Histopathologically, the lesions were composed of numerous plasma cells, lymphocytes, histiocytes, and spindle myofibroblastic cells, showing perineural infiltration of inflammatory cells. The patients’ symptoms, including conductive hearing loss, improved dramatically with reduction in lesion size after corticosteroid treatment.</description><identifier>ISSN: 0385-8146</identifier><identifier>EISSN: 1879-1476</identifier><identifier>DOI: 10.1016/j.anl.2009.08.002</identifier><identifier>PMID: 19857937</identifier><language>eng</language><publisher>Netherlands: Elsevier Ireland Ltd</publisher><subject>Anti-Inflammatory Agents - therapeutic use ; Corticosteroids ; Diagnosis, Differential ; Female ; Granuloma, Plasma Cell - drug therapy ; Granuloma, Plasma Cell - pathology ; Hearing Loss, Conductive - diagnosis ; Humans ; Immunohistochemistry ; Inflammatory pseudotumor ; Magnetic Resonance Imaging ; Middle Aged ; Otolaryngology ; Parapharyngeal space ; Pharyngeal Diseases - drug therapy ; Pharyngeal Diseases - pathology ; Severity of Illness Index</subject><ispartof>Auris, nasus, larynx, 2010-06, Vol.37 (3), p.397-400</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2009 Elsevier Ireland Ltd</rights><rights>Copyright (c) 2009 Elsevier Ireland Ltd. 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The occurrence of inflammatory pseudotumor in the head and neck area is uncommon, especially in the parapharyngeal space. The case of a 54-year-old female with inflammatory pseudotumor of the parapharyngeal space is presented. The patient initially complained of hoarseness, dysarthria, aspiration, and hearing impairment. MRI disclosed an expansive soft mass in the parapharyngeal space encompassing the carotid arteries. Histopathologically, the lesions were composed of numerous plasma cells, lymphocytes, histiocytes, and spindle myofibroblastic cells, showing perineural infiltration of inflammatory cells. The patients’ symptoms, including conductive hearing loss, improved dramatically with reduction in lesion size after corticosteroid treatment.</description><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Corticosteroids</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Granuloma, Plasma Cell - drug therapy</subject><subject>Granuloma, Plasma Cell - pathology</subject><subject>Hearing Loss, Conductive - diagnosis</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Inflammatory pseudotumor</subject><subject>Magnetic Resonance Imaging</subject><subject>Middle Aged</subject><subject>Otolaryngology</subject><subject>Parapharyngeal space</subject><subject>Pharyngeal Diseases - drug therapy</subject><subject>Pharyngeal Diseases - pathology</subject><subject>Severity of Illness Index</subject><issn>0385-8146</issn><issn>1879-1476</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtLxDAUhYMoOj5-gBvpzlXrTdM2iYIwDL5AcKGuQ0xutWPb1KQV5t-bYQYEF67u5pxzOd8h5JRCRoFWF8tM922WA8gMRAaQ75AZFVymtODVLpkBE2UqaFEdkMMQlgDAOJP75IBKUXLJ-IwsHvq61V2nR-dXyRBwsm6cOucTVyfjByaD9nr40H7Vv6NukzBog5fJPDE6YOJxcH48Jnu1bgOebO8Reb29eVncp49Pdw-L-WNqCsnHVEoGOVbMVBZsxTD-t1zWElBgrnnNQUNtSyt1WYo3lqNhNZXa8limqgrOjsj5Jnfw7mvCMKquCQbbVvfopqA4YwXkkJdRSTdK410IHms1-KaLJRQFtUanliqiU2t0CoSK6KLnbJs-vXVofx1bVlFwtRFg7PjdoFfBNNgbtI1HMyrrmn_jr_-4Tdv0jdHtJ64wLN3k-whPURVyBep5vd16OpAAVABlP8-ykx4</recordid><startdate>20100601</startdate><enddate>20100601</enddate><creator>Maruya, Shin-ichiro</creator><creator>Miura, Kouki</creator><creator>Tada, Yu-ichiro</creator><creator>Masubuchi, Tatsuo</creator><creator>Nakamura, Narihiro</creator><creator>Fushimi, Chihiro</creator><creator>Sakashita, Tomohiro</creator><creator>Monma, Tsutomu</creator><creator>Kamata, Shin-etsu</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100601</creationdate><title>Inflammatory pseudotumor of the parapharyngeal space: A case report</title><author>Maruya, Shin-ichiro ; 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The occurrence of inflammatory pseudotumor in the head and neck area is uncommon, especially in the parapharyngeal space. The case of a 54-year-old female with inflammatory pseudotumor of the parapharyngeal space is presented. The patient initially complained of hoarseness, dysarthria, aspiration, and hearing impairment. MRI disclosed an expansive soft mass in the parapharyngeal space encompassing the carotid arteries. Histopathologically, the lesions were composed of numerous plasma cells, lymphocytes, histiocytes, and spindle myofibroblastic cells, showing perineural infiltration of inflammatory cells. The patients’ symptoms, including conductive hearing loss, improved dramatically with reduction in lesion size after corticosteroid treatment.</abstract><cop>Netherlands</cop><pub>Elsevier Ireland Ltd</pub><pmid>19857937</pmid><doi>10.1016/j.anl.2009.08.002</doi><tpages>4</tpages></addata></record> |
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| subjects | Anti-Inflammatory Agents - therapeutic use Corticosteroids Diagnosis, Differential Female Granuloma, Plasma Cell - drug therapy Granuloma, Plasma Cell - pathology Hearing Loss, Conductive - diagnosis Humans Immunohistochemistry Inflammatory pseudotumor Magnetic Resonance Imaging Middle Aged Otolaryngology Parapharyngeal space Pharyngeal Diseases - drug therapy Pharyngeal Diseases - pathology Severity of Illness Index |
| title | Inflammatory pseudotumor of the parapharyngeal space: A case report |
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