Basement membranes: structure, assembly and role in tumour angiogenesis

Key Points Vascular basement membranes (BMs) are important structural and functional components of all blood vessels/capillaries and have a crucial role in determining the progression of cancer. Constituents of vascular BMs, such as type IV collagen, laminin, SPARC and perlecan, have emerged as key...

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Veröffentlicht in:	Nature reviews. Cancer 2003-06, Vol.3 (6), p.422-433
1. Verfasser:	Kalluri, Raghu
Format:	Artikel
Sprache:	eng
Schlagworte:	Basement Membrane - metabolism Basement Membrane - ultrastructure Biomedical and Life Sciences Biomedicine Cancer Research Capillaries - physiology Cell membranes Collagen - metabolism Control Endothelium, Vascular - metabolism Extracellular Matrix - metabolism Extracellular Matrix Proteins - metabolism Forecasting Genetic aspects Neoplasms - blood supply Neoplasms - pathology Neovascularization Neovascularization, Pathologic - pathology Physiological aspects review-article Risk factors Structure Tumors
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