Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure

Exercise training has been reported to exert beneficial effects on cardiac function and to reduce morbidity and mortality of chronic heart failure (HF). Augmented sympathetic nervous system (SNS) activity, leading to elevated circulating catecholamine (CA) levels, is a hallmark of chronic HF that si...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2010-06, Vol.298 (6), p.H2032-H2038
Hauptverfasser: Rengo, Giuseppe, Leosco, Dario, Zincarelli, Carmela, Marchese, Massimo, Corbi, Graziamaria, Liccardo, Daniela, Filippelli, Amelia, Ferrara, Nicola, Lisanti, Michael P, Koch, Walter J, Lymperopoulos, Anastasios
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Sprache:eng
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