(-)-epigallocatechin-3-gallate reduces experimental colon injury in rats by regulating macrophage and mast cell

The ameliorative effect of (-)-epigallocatechin-3-gallate (EGCG) on inflammatory bowel disease (IBD) induced by ethanol 2,4,6-trinitrobenzene sulfonic acid (TNBS) was studied in 7-week-old male rats. Intestinal lesions were measured as an increase in myeloperoxidase (MPO) activity in mucosa. The sup...

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Veröffentlicht in:	Phytotherapy research 2010, Vol.24 (S1), p.S120-S122
Hauptverfasser:	Mochizuki, Miyako, Hasegawa, Noboru
Format:	Artikel
Sprache:	eng
Schlagworte:	(-)-epigallocatechin-3-gallate 2,4,6‐trinitorobenzene sulfonic acid 6-trinitorobenzene sulfonic acid Animals Catechin - analogs & derivatives Catechin - pharmacology Chemotaxis - drug effects Colitis - chemically induced Colitis - drug therapy Colitis - pathology histamine Histamine - metabolism inflammatory bowel disease macrophage Macrophages - drug effects Male Mast Cells - drug effects myeloperoxidase N-Formylmethionine Leucyl-Phenylalanine Peroxidase - metabolism Rats Rats, Sprague-Dawley Trinitrobenzenesulfonic Acid
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